Search

Displaying results 6511 - 6520 of 7067 in total
  1. Drug

    Delamanid

    go.drugbank.com/drugs/DB11637
    ApprovedInvestigational

    It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. … Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for patients, as the disease is associated with a higher mortality rate and insufficient therapeutic

  2. Drug

    Benfotiamine

    go.drugbank.com/drugs/DB11748
    ApprovedInvestigationalWithdrawn

    Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.

    Categories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  3. Drug

    Tosedostat

    go.drugbank.com/drugs/DB11781
    Investigational

    It has demonstrated anti-tumour activity in a number of models of cancer, both as a single agent and in synergy with cytotoxic agents such as carboplatin and paclitaxel.

  4. Drug

    Anisodamine

    go.drugbank.com/drugs/DB11785
    Investigational

    Anisodamine has been investigated for the treatment of Intestinal Diseases.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Dinitrochlorobenzene

    go.drugbank.com/drugs/DB11831
    Investigational

    Dinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Astodrimer

    go.drugbank.com/drugs/DB11854
    Investigational

    It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Vosoritide

    go.drugbank.com/drugs/DB11928
    ApprovedInvestigational

    of a peptidase-resistant formulation has allowed for its use as a viable treatment option in achondroplasia. … [A242277] It results from a gain-of-function missense mutation in _FGFR3_ that results in a dramatic suppression of bone growth, both in volume and in length.

  8. Drug

    Abametapir

    go.drugbank.com/drugs/DB11932
    Approved

    Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice. … [A216183] Topical pediculicides generally lack adequate ovicidal activity,[A216183] including standard-of-care treatments such as [permethrin], and many require a second administration 7-10 days following

  9. Drug

    Tesevatinib

    go.drugbank.com/drugs/DB11973
    Investigational

    Tesevatinib inhibits the EGF, HER2, and VEGF RTKs, each of which is a target of currently approved cancer therapies. … In addition, tesevatinib inhibits EphB4, an RTK that is highly expressed in many human tumors and plays a role in promoting angiogenesis.

  10. Drug

    Diacerein

    go.drugbank.com/drugs/DB11994
    ApprovedInvestigationalWithdrawn

    Diacerein is a prodrug which is metabolized to rhein.