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Methoxamine
go.drugbank.com/drugs/DB00723ApprovedInvestigationalWithdrawnAn alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
MaxAdFVIII
go.drugbank.com/drugs/DB17713ExperimentalFirst developed by GenStar, it is being investigated for the treatment of hemophilia.
Befunolol
go.drugbank.com/drugs/DB09013ExperimentalBefunolol is a beta blocker introduced in 1983 by Kakenyaku Kakko. It is currently in experimental status, and is being tested for the management of open angle glaucoma.
Cirazoline
go.drugbank.com/drugs/DB09202ExperimentalCirazoline has also been shown to decrease food intake in rats, purportedly through activation of α1-adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain.
Lotiglipron
go.drugbank.com/drugs/DB21631InvestigationalLotiglipron is under investigation in clinical trial NCT05579977 (Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People
CRx-139
go.drugbank.com/drugs/DB05744ExperimentalIt is a dissociated steroid designed to enhance the immuno-modulatory activity of a low-dose glucocorticoid steroid without a comparable increase in steroid-related side effects.
SVV-001
go.drugbank.com/drugs/DB06129InvestigationalSVV-001 has also demonstrated cancer-killing specificity 10,000 times higher than that of traditional chemotherapeutics with no overt toxicity at doses one million times higher than effective doses in
Flizasertib
go.drugbank.com/drugs/DB21613InvestigationalFlizasertib is under investigation in clinical trial NCT06602453 (A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse
Eritoran
go.drugbank.com/drugs/DB04933InvestigationalIt is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Dipropyl-4-hydroxytryptamine
go.drugbank.com/drugs/DB13990ExperimentalDipropyl-4-hydroxytryptamine was first synthesized by Alexander Shulgin. This agent and its properties haven't been fully elucidated.
Synonyms: 4-HO-DPT, 4-Hydroxy-N,N-dipropyltryptamine