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ATP
go.drugbank.com/drugs/DB00171InvestigationalNutraceuticalAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Categories: Nucleic Acids, Nucleotides, and NucleosidesDavalintide
go.drugbank.com/drugs/DB14956InvestigationalDavalintide is under investigation in clinical trial NCT00785408 (Study to Examine Safety, Tolerability and Effect on Body Weight of Subcutaneous AC2307 in Obese or Overweight Subjects).
Categories: Amino Acids, Peptides, and ProteinsNocodazole
go.drugbank.com/drugs/DB08313ExperimentalNocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.
Valanafusp alfa
go.drugbank.com/drugs/DB15336InvestigationalValanafusp alfa is under investigation in clinical trial NCT03071341 (Extension Study Evaluating Long Term Safety and Activity of AGT-181 in Children With MPS I).
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsMPT0B640
go.drugbank.com/drugs/DB16512InvestigationalMPT0B640 was under investigation in clinical trials NCT04526717 for COVID-19 infection and NCT04294875 for locally advanced or metastatic solid malignancies.
Triciribine
go.drugbank.com/drugs/DB12405InvestigationalTriciribine has been used in trials studying the treatment of Leukemia, Ovarian Cancer, HER2/Neu Negative, Breast Adenocarcinoma, and Stage IV Breast Cancer, among others.
Categories: Nucleic Acids, Nucleotides, and NucleosidesADL 10-0101
go.drugbank.com/drugs/DB05443ExperimentalPreclinical trials of ADL 10-0101 have suggested that the compound may be effective for the treatment of inflammatory pain, itch and visceral pain. … Because ADL 10-0101 does not cross the blood-brain barrier and enter the brain when administered at therapeutic doses, it is expected to avoid central nervous system side effects.
Fezakinumab
go.drugbank.com/drugs/DB12344InvestigationalFezakinumab has been used in trials studying the treatment of Atopic Dermatitis and Rheumatoid Arthritis.
Categories: Amino Acids, Peptides, and ProteinsRociletinib
go.drugbank.com/drugs/DB11907InvestigationalRociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Categories: Antineoplastic and Immunomodulating AgentsRifalazil
go.drugbank.com/drugs/DB04934InvestigationalIt is being investigated by ActivBiotics for the treatment of various bacterial infections.