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Displaying results 6581 - 6590 of 10000 in total
  1. Drug

    Captodiame

    go.drugbank.com/drugs/DB09014
    Experimental

    Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine.

  2. Drug

    AZD-2836

    go.drugbank.com/drugs/DB06031
    Investigational

    AZD-2836 is an inhibitor of the nonstructural protein 5A (NS5A).[A264853] The drug is being investigated for treatment of hepatitis C because AZD-2836 has in vitro anti-HCV activity.[A264858]

  3. Drug

    Emeramide

    go.drugbank.com/drugs/DB12192
    Investigational

    Emeramide has been used in trials studying the treatment of Mercury Poisoning.

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Empesertib

    go.drugbank.com/drugs/DB19473
    Investigational

    Empesertib has a monoisotopic molecular weight of 559.17 Da. … Empesertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Empesertib is a serine/threonine kinase inhibitor.

  5. Drug

    Mevociclib

    go.drugbank.com/drugs/DB21454
    Investigational

    Mevociclib is under investigation in clinical trial NCT03134638 (A Study of SY-1365 in Adult Patients With Advanced Solid Tumors). Mevociclib has a monoisotopic molecular weight of 586.26 Da. … Mevociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Mevociclib is a cyclin dependant kinase inhibitor.

  6. Drug

    Risvodetinib

    go.drugbank.com/drugs/DB21602
    Investigational

    Risvodetinib has a monoisotopic molecular weight of 574.28 Da. … Risvodetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Risvodetinib is a tyrosine kinase inhibitor.

  7. Drug

    QRX-411

    go.drugbank.com/drugs/DB17868
    Experimental

    It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.

  8. Drug

    Zatolmilast

    go.drugbank.com/drugs/DB14790
    Investigational

    BPN-14770 is under investigation in clinical trial NCT02840279 (A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects).

    Categories: Small Molecule Allosteric Inhibitor of the Phosphodiesterase-4D Enzyme
  9. Drug

    Indole-3-carbinol

    go.drugbank.com/drugs/DB12881
    Investigational

    Indole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Cediranib

    go.drugbank.com/drugs/DB04849
    Investigational

    It is being developed clinically as a once-daily oral therapy for the treatment of cancer. … The novel indole-ether quinazoline Cediranib is a highly potent (IC<sub>50</sub> &lt; 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro.