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Displaying results 6581 - 6590 of 10000 in total
  1. Target

    Histone acetyltransferase KAT2B

    go.drugbank.com/bio_entities/BE0002683
    TargetHumans

    Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5 (PubMed:29174768). … Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles (PubMed:8945521).

    Synonyms: P/CAF
  2. Drug

    XmAb 2513

    go.drugbank.com/drugs/DB06324
    Investigational

    XmAb 2513 is a humanized monoclonal antibody that targets the antigen CD30, a molecule expressed on the surface of a number of tumor cell types. … It has been investigated for the treatment of hodgkin’s lymphoma.

    Categories: Amino Acids, Peptides, and Proteins
  3. Drug

    Coconut oil

    go.drugbank.com/drugs/DB14322
    Investigational

    Coconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Hair Loss and Scalp Moisturizing
  4. Drug

    FG-2216

    go.drugbank.com/drugs/DB08687
    Investigational

    A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability. [A14422]

    Synonyms: 1-Chloro-N- (hydroxyformylmethyl-4-hydroxyisoquinoline-3-carboxamide, 1-Chloro-N-(hydroxyformylmethyl-4-hydroxyisoquinoline-3-carboxamide
  5. Drug

    GX-19 Vaccine

    go.drugbank.com/drugs/DB15891
    Investigational

    The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. … As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].

  6. Drug

    Rocatinlimab

    go.drugbank.com/drugs/DB18809
    Investigational

    In clinical trials, it has shown significant efficacy and safety compared to a placebo. … The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis.

    Categories: Amino Acids, Peptides, and Proteins
  7. Drug

    Ipragliflozin

    go.drugbank.com/drugs/DB11698
    Investigational

    Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.

    Categories: Drugs Used in Diabetes, Alimentary Tract and Metabolism
  8. Indication

    Fallopian Tube Cancer

    go.drugbank.com/conditions/DBCOND0028487
    Drugs: Paclitaxel
    Synonyms: Fallopian tube Ca
  9. Drug

    Furvina

    go.drugbank.com/drugs/DB16547
    Experimental

    Furvina (G1) is an antimicrobial agent active against Gram-positive and Gram-negative bacteria, yeasts, and filamentous fungi. … Furvina is marketed in Cuba as Dermofural®, an ointment containing G1 as the only active principle ingredient. It is used to treat dermatological infections.[A228063]

  10. Drug

    SCIB1

    go.drugbank.com/drugs/DB18439
    Investigational

    SCIB1 is an investigational cancer vaccine being developed by Scancell Ltd. It is being investigated for the treatment of melanoma. … It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cells to have a stronger reaction against melanoma cells.