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CA-074 methyl ester
go.drugbank.com/drugs/DB07223ExperimentalIt is converted by cellular esterases to CA-074.[A258234,A258239]
Categories: Amino Acids, Peptides, and ProteinsEMZ702
go.drugbank.com/drugs/DB05021Investigationalcompared to interferon and ribavirin alone. … EMZ702 has an excellent safety profile and the combination of EMZ702 with interferon and ribavirin in surrogate models for hepatitis C has demonstrated a two to three fold increase in anti-viral potency
Lorukafusp alfa
go.drugbank.com/drugs/DB15443InvestigationalLorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma).
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsThiorphan
go.drugbank.com/drugs/DB08626ExperimentalThiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
Categories: Amino Acids, Peptides, and ProteinsHemoglobin glutamer-256 (human)
go.drugbank.com/drugs/DB19285InvestigationalHemoglobin glutamer-256 (human) is under investigation in clinical trial NCT00076648 (Safety and Efficacy of Polyheme(r) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-hospital
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsRDEA806
go.drugbank.com/drugs/DB05228InvestigationalRDEA806 is a new HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with a high genetic barrier to resistance and a broad spectrum of activity.
Balovaptan
go.drugbank.com/drugs/DB14823InvestigationalBalovaptan is under investigation in clinical trial NCT01793441 (A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)).
Peginterferon lambda-1a
go.drugbank.com/drugs/DB14767InvestigationalPeginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs.
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsGevokizumab
go.drugbank.com/drugs/DB12119InvestigationalIt has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.
Categories: Amino Acids, Peptides, and ProteinsArbaclofen
go.drugbank.com/drugs/DB08891InvestigationalIt is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind … It has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord injury.