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Displaying results 6621 - 6630 of 10000 in total
  1. Drug

    PRLX 93936

    go.drugbank.com/drugs/DB06098
    Investigational

    PRLX 93936 is selectively toxic to cancer cells.

  2. Drug

    Resatorvid

    go.drugbank.com/drugs/DB05943
    Investigational

    Resatorvid is an investigational compound designed for the treatment of severe sepsis.

  3. Drug

    ZYCOV-D

    go.drugbank.com/drugs/DB15892
    Experimental

    Once the plasmid DNA is introduced into host cells and the viral protein is translated, it elicits a strong immune response, stimulating the humoral and cellular components of the immune system[L16503] … As of August, 2020 the candidate is in Phase II clinical trials[A219758].

  4. Drug

    N-Formylmethionine

    go.drugbank.com/drugs/DB04464
    Experimental

    N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. … This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.

    Synonyms: (2S)-2-(formylamino)-4-(methylthio)butanoic acid, L-N-Formylmethionine
  5. Drug

    Aldosterone

    go.drugbank.com/drugs/DB04630
    Investigational

    A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

    Categories: P-glycoprotein inducers, P-glycoprotein substratesSynonyms: (11β)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al, 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al
  6. Drug

    Sizofiran

    go.drugbank.com/drugs/DB13128
    Investigational

    A beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. … Sizofiran has been used in trials studying the treatment of Cervical Cancer.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    GTI-2501

    go.drugbank.com/drugs/DB05406
    Experimental

    The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer. … GTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial.

  8. Drug

    AZD 3355

    go.drugbank.com/drugs/DB05404
    Investigational

    AZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. It is developed by AstraZeneca and is currently in phase I/II trials.

    Categories: GABA-A Receptor Agonists
  9. Drug

    KP-1461

    go.drugbank.com/drugs/DB05644
    Investigational

    Designated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases. … KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue.

  10. Drug

    Citatuzumab Bogatox

    go.drugbank.com/drugs/DB06072
    Investigational

    VB6-845 is a humanized antibody fragment targeting EpCAM fused with the deimmunized form of the cytotoxin Bouganin and is designed for systemic use against metastatic cancer.