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Displaying results 6621 - 6630 of 10000 in total
  1. Drug

    Gevokizumab

    go.drugbank.com/drugs/DB12119
    Investigational

    It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.

    Categories: Amino Acids, Peptides, and Proteins
  2. Drug

    L523S

    go.drugbank.com/drugs/DB06498
    Investigational

    and when delivered following incorporation into an E1B-deleted adenovirus (Ad/L523S)." … According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S)

  3. Drug

    Setiptiline

    go.drugbank.com/drugs/DB09304
    Experimental

    Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).

  4. Drug

    Tienilic acid

    go.drugbank.com/drugs/DB04831
    ApprovedWithdrawn

    It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)

  5. Drug

    Dimetacrine

    go.drugbank.com/drugs/DB08996
    ApprovedWithdrawn

    It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil.

  6. Drug

    Procizumab

    go.drugbank.com/drugs/DB23041
    Investigational

    Procizumab is under investigation in clinical trial NCT06331884 (Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics/-Dynamics of AK1967 (Procizumab)).

    Categories: Amino Acids, Peptides, and Proteins
  7. Drug

    Abelacimab

    go.drugbank.com/drugs/DB16682
    Investigational

    Abelacimab is under investigation in clinical trial NCT04755283 (Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation).

    Categories: Amino Acids, Peptides, and Proteins
  8. Drug

    Epirizole

    go.drugbank.com/drugs/DB08991
    Experimental

    Epirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.

  9. Drug

    Mongersen

    go.drugbank.com/drugs/DB15019
    Investigational

    Mongersen is under investigation in clinical trial NCT02957474 (A Study to Evaluate the Effect of Food, Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  10. Drug

    Tarextumab

    go.drugbank.com/drugs/DB12104
    Investigational

    Tarextumab has been used in trials studying the treatment of Solid Tumors, Stage IV Pancreatic Cancer, and Stage IV Small Cell Lung Cancer.

    Categories: Amino Acids, Peptides, and Proteins