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Mesterolone
go.drugbank.com/drugs/DB13587InvestigationalMesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH [A27177, A27178]. … It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen.
Captodiame
go.drugbank.com/drugs/DB09014ExperimentalCaptodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. … Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Synonyms: 2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamineLibivirumab
go.drugbank.com/drugs/DB17748ExperimentalIt is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.[A259202] … Libivirumab is an investigational monoclonal antibody.
IDM-4
go.drugbank.com/drugs/DB05438ExperimentalIDM-4 is an immuno-designed molecule that completed phase I/II of investigation for the treatment of Leukemia. … It is a monoclonal antibody-specific antigen that can selectively target cancer-affected cells by coupling with tumor cell-killing MAK cells, which are derived from the patient's own monocytes.
AT1391
go.drugbank.com/drugs/DB05120ExperimentalAT1391 is a daily insulin skin patch designed to provide continuous basal levels of insulin for patients with diabetes.
Amdizalisib
go.drugbank.com/drugs/DB21514InvestigationalAmdizalisib is under investigation in clinical trial NCT05713110 (A Study of Tazemetostat in Combination With HMPL-689 in Patients With Relapsed/Refractory Lymphoma). … Amdizalisib has a monoisotopic molecular weight of 390.11 Da.
Rimacalib
go.drugbank.com/drugs/DB12571InvestigationalRimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).
Totrombopag
go.drugbank.com/drugs/DB05930Investigational, thus representing a significant problem in the treatment of cancer patients. … SB-559448 is a small-molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor that promotes growth and production of blood platelets.