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Zeprumetostat
go.drugbank.com/drugs/DB21740InvestigationalThe usage of the INN stem '-metostat' in the name indicates that Zeprumetostat is a histone N-methyltransferase inhibitor. Zeprumetostat has a monoisotopic molecular weight of 548.34 Da.
Seproxetine
go.drugbank.com/drugs/DB06731ExperimentalIt is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and the drug was never marketed.
Endostar
go.drugbank.com/drugs/DB11727InvestigationalEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Modithromycin
go.drugbank.com/drugs/DB16238InvestigationalModithromycin is under investigation in clinical trial NCT00270517 (Comparative Study of EDP-420 Versus Another Antibiotic in the Treatment of Community Acquired Pneumonia).
Ribaxamase
go.drugbank.com/drugs/DB16311InvestigationalRibaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
BNT111
go.drugbank.com/drugs/DB18177InvestigationalIt consists of a fixed combination of mRNA-encoded, tumor-associated antigens.
GW-468816
go.drugbank.com/drugs/DB15099ExperimentalGW-468816 is under investigation in clinical trial NCT00218465 (Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking).
Chitin
go.drugbank.com/drugs/DB15142InvestigationalShrimp shell chitin is under investigation in clinical trial NCT00863356 (Trial of a Novel Chitosan Hemostatic Sealant in the Management of Complicated Epistaxis).
ARC-19499
go.drugbank.com/drugs/DB15285InvestigationalARC-19499 is under investigation in clinical trial NCT01191372 (First-in-Human and Proof-of-Mechanism Study of ARC19499 Administered to Hemophilia Patients).
Monalizumab
go.drugbank.com/drugs/DB12824InvestigationalMonalizumab has been used in trials studying the treatment of Gynecologic Cancer, Chronic Lymphocytic Leukemia, and Squamous Cell Carcinoma of the Oral Cavity.