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Verteporfin
go.drugbank.com/drugs/DB00460ApprovedInvestigationalVerteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: CL-315555 and CL-315585. It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form...
Products: VISUDYNE FOR INJECTION 15 mg/vialDantrolene
go.drugbank.com/drugs/DB01219ApprovedInvestigationalChemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Synonyms: 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoinProducts: Dantrolene Sodium for Injection, USP, Dantrolen i.v. 20 mg Pulver zur Herstellung einer Injektions-/InfusionslösungMebrofenin
go.drugbank.com/drugs/DB15779ApprovedProducts: Kit for the Preparation of Technetium Tc 99m MebrofeninBuserelin
go.drugbank.com/drugs/DB06719ApprovedInvestigationalBuserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR).
Products: Suprefact Depot - Implantat für 3 MonateCefotaxime
go.drugbank.com/drugs/DB00493ApprovedInvestigationalCefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to c...
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: CYTAXIN POWDER FOR SOLUTION FOR INJECTION 1G/VIAL, CYTAXIN POWDER FOR SOLUTION FOR INJECTION 0.5G/VIALZopiclone
go.drugbank.com/drugs/DB01198ApprovedInvestigationalZopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbitu...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Mar-zopicloneCabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigational[L31198] While previously administered once monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine].
Categories: P-glycoprotein substrates, Antivirals for Systemic UseProducts: Apretude 600mg Prolonged-release suspension for injectionTerazosin
go.drugbank.com/drugs/DB01162ApprovedInvestigationalTerazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label][A176831].
Categories: P-glycoprotein inhibitors, Antihypertensive Agents Indicated for HypertensionProducts: FLOTRIN 10MG MAXOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigational[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and … [A183782,L8648] This drug relieves undesirable urinary symptoms, increasing the quality of life for patients affected by OAB. It is often used as first-line therapy for OAB.[A185990]
Categories: Drugs for Urinary Frequency and Incontinence, Cytochrome P-450 SubstratesProducts: Oxytrol For Women, Oxytrol for WomenGalsulfase
go.drugbank.com/drugs/DB01279ApprovedInvestigationalThe recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular … Post-translational modification of Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family
Products: Naglazyme Concentrated Solution for Intravenous Infusion 1mg/1ml