Search

Displaying results 661 - 670 of 10000 in total
  1. Drug

    Palbociclib

    go.drugbank.com/drugs/DB09073
    ApprovedInvestigational

    [L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and its indications were updated in April 2019 to include male … [A176810] Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as key regulators of cell growth.

    Products: PMS-palbociclib
  2. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids. … It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA).

    Products: BENEPALI 50MG ILO I E FER, ENBREL MYCLIC PEN 50 MG ENJ. COZ.ICIN KULLANIMA HAZIR KALEM, 12 ADET
  3. Drug

    Montelukast

    go.drugbank.com/drugs/DB00471
    ApprovedInvestigational

    Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. … worldwide via millions of prescriptions annually and has since become available as a generic and as a brand name product.

    Synonyms: (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acidProducts: MONTELUKAST EG, PMS-montelukast
  4. Drug

    Coagulation Factor IX Human

    go.drugbank.com/drugs/DB13152
    ApprovedInvestigational

    Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.

    Mixtures: Beriplex P/n 500, Beriplex P/n 1000Categories: coagulation factor IX, II, VII and X in combination
  5. Drug

    Tenofovir disoproxil

    go.drugbank.com/drugs/DB00300
    ApprovedInvestigational

    This drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label]. … Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase

    Mixtures: PMS-emtricitabine-tenofovir, PMS-efavirenz-emtricitabine-tenofovirCategories: Antivirals used in combination for the treatment of HIV infections
  6. Drug

    Fluorouracil

    go.drugbank.com/drugs/DB00544
    ApprovedInvestigational

    A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.

    Products: 5-FLUOROURACIL 1000 MG/20 ML ENJ. COZ. ICIN FLAKON, 5-FLUOROURACIL EBEWE 500 MG/10 ML ENJ. ICIN COZ. ICEREN FLAKON
  7. Drug

    Mometasone

    go.drugbank.com/drugs/DB00764
    ApprovedInvestigational

    Mometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.

    Products: MOMETASONE EG
  8. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008. … [A262681] It was granted approval by Health Canada in September 2010.[L49206]

    Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEProducts: PMS-lacosamide, LACOSAMIDE EG
  9. Drug

    Ceftriaxone

    go.drugbank.com/drugs/DB01212
    ApprovedInvestigational

    [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627]. … Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus.

    Products: CEFTRIAXONE EG, Rocephin Pws 2gm/vial
  10. Drug

    Gemfibrozil

    go.drugbank.com/drugs/DB01241
    ApprovedInvestigational

    [L8525] Gemfibrozil was granted FDA approval on 21 December 1981.[L8525] … [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications.

    International brands: Gen-FibroProducts: PMS-gemfibrozil