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Docosanol
go.drugbank.com/drugs/DB00632ApprovedDocosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid e...
Synonyms: N-DocosanolAnti-SARS-CoV-2 IgY
go.drugbank.com/drugs/DB16356Investigational[L27381] To create these antibodies, chickens are injected in the chest with the spike protein, which is the surface protein of SARS-CoV-2; this results in an immune response mounted by the chickens towards … These antibodies are currently being investigated against COVID-19 in the trial NCT04567810 (Safety, Tolerability, and Pharmacokinetics of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV
Kitasamycin
go.drugbank.com/drugs/DB09309ExperimentalKitasamycin is a macrolide antibiotic derived from <em>Streptomyces kitasatoensis</em>.
Fosifloxuridine nafalbenamide
go.drugbank.com/drugs/DB14859InvestigationalFosifloxuridine nafalbenamide is under investigation in clinical trial NCT03428958 (A Safety Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment).
Ieramilimab
go.drugbank.com/drugs/DB16419InvestigationalIeramilimab is under investigation in clinical trial NCT02460224 (Safety and Efficacy of LAG525 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.).
Pidotimod
go.drugbank.com/drugs/DB11364InvestigationalPidotimod is a synthetic dipeptide with immunomodulatory properties.
Mericitabine
go.drugbank.com/drugs/DB12045InvestigationalMericitabine is a prodrug of PSI-6130, which demonstrated excellent potency in preclinical studies. … PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an enzyme that is necessary for hepatitis C viral replication.
Fenbufen
go.drugbank.com/drugs/DB08981ApprovedFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.
Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen
go.drugbank.com/drugs/DB15683ApprovedInvestigationalAmcipatricin
go.drugbank.com/drugs/DB12333InvestigationalIn preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp. … SPK-843 exhibits dose-dependent efficacy on murine pulmonary aspergillosis models.