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Adlinacogene civaparvovec
go.drugbank.com/drugs/DB16788Investigational[L46711] Developed by Sangamo Therapeutics Inc., it is being investigated for the treatment of hemophilia B.[L46706] … It uses proprietary zinc finger nuclease (ZFN) genome editing to insert into the DNA of liver cells a copy of the F9 gene, which controls the production of Factor IX.
Protriptyline
go.drugbank.com/drugs/DB00344ApprovedIn non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive effect on mood. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.
Synonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamineNigella sativa oil
go.drugbank.com/drugs/DB28165InvestigationalNigella Sativa Oil is a biologic drug. … Nigella Sativa Oil is under investigation in clinical trial NCT06823544 (A Comparative Single Blind Clinical Study on the Effect of Alvogyl, Eugenol, and Nigella Sativa (Black Seed Oil) for Alveolar Osteitis
Synonyms: Black Seed Oil, Nigella Sativa OilDesmethylprodine
go.drugbank.com/drugs/DB01478ExperimentalIllicitIt has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. … Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine.
Caramiphen
go.drugbank.com/drugs/DB11504ExperimentalVet approvedCaramiphen is a cholinergic antagonist used in Parkinson's disease. … Additionally, it is used, in combination with [phenylpropanolamine], as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.
Deanol
go.drugbank.com/drugs/DB13352InvestigationalIt has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products. … Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups.
Maropitant
go.drugbank.com/drugs/DB11427ExperimentalVet approvedIt was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats. … Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs.
Inositol 1,3-bisphosphate
go.drugbank.com/drugs/DB02942ExperimentalIt is an experimental compound with no approved therapeutic indications. … It has molecular formula C6H14O12P2 and is categorized as a sugar phosphate/sugar alcohol.
Panax ginseng fruit
go.drugbank.com/drugs/DB14261InvestigationalPanax ginseng fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Maclura tricuspidata whole
go.drugbank.com/drugs/DB14264InvestigationalMaclura tricuspidata whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.