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Displaying results 6741 - 6750 of 10000 in total
  1. Drug

    1D-myo-inositol 1,4,5-trisphosphate

    go.drugbank.com/drugs/DB03401
    Experimental

    Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. … Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum.

  2. Drug

    Theofibrate

    go.drugbank.com/drugs/DB19587
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Theofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … The usage of the INN stem '-fylline' in the name indicates that Theofibrate is a N-methylated xanthine derivative.

  3. Drug

    Norfloxacin succinil

    go.drugbank.com/drugs/DB20858
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Norfloxacin succinil is a benzodiazepine receptor antagonist/agonist. … The usage of the INN stem '-oxacin' in the name indicates that Norfloxacin succinil is a nalidixic acid derivative antibacterial. Norfloxacin succinil has a monoisotopic molecular weight of 419.15 Da.

  4. Drug

    Matuzumab

    go.drugbank.com/drugs/DB05101
    Investigational

    It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival. … Matuzumab (formerly known as the experimental drug, EMD 72000) is a humanized monoclonal antibody used in cancer treatment.

  5. Drug

    Ribuvaptan

    go.drugbank.com/drugs/DB20059
    Experimental

    The usage of the INN stem '-vaptan' in the name indicates that Ribuvaptan is a vasopressin receptor antagonist. Ribuvaptan has a monoisotopic molecular weight of 595.11 Da.

  6. Drug

    Fasobegron

    go.drugbank.com/drugs/DB20200
    Experimental

    The usage of the INN stem '-begron' in the name indicates that Fasobegron is a β3​ adrenoreceptor agonists. Fasobegron has a monoisotopic molecular weight of 425.14 Da.

  7. Drug

    Ruclosporin

    go.drugbank.com/drugs/DB21199
    Experimental

    The usage of the INN stem '-(clo)sporin' in the name indicates that Ruclosporin is a cyclosporine derivative. Ruclosporin has a monoisotopic molecular weight of 1330.92 Da.

  8. Drug

    Filapixant

    go.drugbank.com/drugs/DB21467
    Experimental

    The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. Filapixant has a monoisotopic molecular weight of 521.17 Da.

  9. Drug

    Teplinovivint

    go.drugbank.com/drugs/DB21475
    Experimental

    The usage of the INN stem '-vivint' in the name indicates that Teplinovivint is a Wnt signaling inhibitor. Teplinovivint has a monoisotopic molecular weight of 442.21 Da.

  10. Drug

    Ipivivint

    go.drugbank.com/drugs/DB21479
    Experimental

    The usage of the INN stem '-vivint' in the name indicates that Ipivivint is a Wnt signaling inhibitor. Ipivivint has a monoisotopic molecular weight of 464.19 Da.