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Displaying results 6761 - 6770 of 10000 in total
  1. Drug

    1D-myo-inositol 1,4,5-trisphosphate

    go.drugbank.com/drugs/DB03401
    Experimental

    Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. … Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum.

  2. Drug

    Theofibrate

    go.drugbank.com/drugs/DB19587
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Theofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … The usage of the INN stem '-fylline' in the name indicates that Theofibrate is a N-methylated xanthine derivative.

  3. Drug

    Norfloxacin succinil

    go.drugbank.com/drugs/DB20858
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Norfloxacin succinil is a benzodiazepine receptor antagonist/agonist. … The usage of the INN stem '-oxacin' in the name indicates that Norfloxacin succinil is a nalidixic acid derivative antibacterial. Norfloxacin succinil has a monoisotopic molecular weight of 419.15 Da.

  4. Drug

    HZT-501

    go.drugbank.com/drugs/DB05369
    Investigational

    HZT-501 is a combination product including ibuprofen and the acid reducing agent famotidine. … It has entered Phase 3 clinical trials in March 2007 for reduction of the risk of development of ibuprofen-associated upper gastrointestinal (i.e., gastric and/or duodenal) ulcers.

  5. Drug

    Ulimorelin

    go.drugbank.com/drugs/DB12128
    Investigational

    Ulimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility of the

  6. Drug

    RUTI® Vaccine

    go.drugbank.com/drugs/DB15853
    Investigational

    Much like the BCG vaccine, the RUTI® vaccine is also being tested as a prophylactic for SARS-CoV2. … The vaccine has demonstrated a reasonable safety profile and potent stimulation of the immune response against tuberculosis.

  7. Drug

    Amediplase

    go.drugbank.com/drugs/DB06679
    Experimental

    Amediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase.

  8. Drug

    2'-Deoxyuridine

    go.drugbank.com/drugs/DB02256
    Investigational

    Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. [PubChem] … An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis.

  9. Drug

    Fosazepam

    go.drugbank.com/drugs/DB19580
    Experimental

    The usage of the INN stem '-azepam' in the name indicates that Fosazepam is a diazepam derivative. Fosazepam has a monoisotopic molecular weight of 360.08 Da.

  10. Drug

    Fomocaine

    go.drugbank.com/drugs/DB19969
    Experimental

    The usage of the INN stem '-caine' in the name indicates that Fomocaine is a local anaesthetic. Fomocaine has a monoisotopic molecular weight of 311.19 Da.