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Displaying results 671 - 680 of 10000 in total
  1. Indication

    Phenylketonuria (PKU)

    go.drugbank.com/conditions/DBCOND0058086
    Drugs: Pegvaliase
    Synonyms: Hyperphenylalaninaemia, Type I, Hyperphenylalaninemia, type I
  2. Drug

    Warfarin

    go.drugbank.com/drugs/DB00682
    ApprovedInvestigational

    Warfarin does not actually affect blood viscosity, rather, it inhibits vitamin-k dependent synthesis of biologically active forms of various clotting factors in addition to several regulatory factors. … Warfarin has several properties that should be noted when used medicinally, including its ability to cross the placental barrier during pregnancy which can result in fetal bleeding, spontaneous abortion

    Categories: Vitamin K Inhibitors, Vitamin K AntagonistsSynonyms: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
  3. Drug

    Anti-CD7 CAR T-cell therapy

    go.drugbank.com/drugs/DB18128
    Experimental

    Synonyms: Anti-CD7 CAR T-cell therapy, A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7
  4. Drug

    Flutamide

    go.drugbank.com/drugs/DB00499
    ApprovedInvestigational

    An antiandrogen with about the same potency as cyproterone in rodent and canine species.

    Categories: Antiandrogens, non-steroidal, Cytochrome P-450 SubstratesSynonyms: α,α,α-trifluoro-2-methyl-4'-nitro-m-propionotoluidide, 4'-nitro-3'-trifluoromethylisobutyranilide
  5. Drug

    Propafenone

    go.drugbank.com/drugs/DB01182
    ApprovedInvestigational

    An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.

    Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IcSynonyms: 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone, 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenone
  6. Drug

    Bimatoprost

    go.drugbank.com/drugs/DB00905
    ApprovedInvestigational

    Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. … [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug

    Mixtures: GANFORT® UD SOLUCION OFTALMICA, BimatoTim-Vision sine 0,3 mg/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisCategories: Cytochrome P-450 Substrates, Prostaglandins F, Synthetic
  7. Drug

    PBCAR20A

    go.drugbank.com/drugs/DB17189
    Investigational

    Synonyms: Allogeneic anti-CD20 CAR T cells, Allogeneic gene edited CD20-directed CAR (Chimeric Antigen Receptor) T cells
  8. Drug

    Fluorometholone

    go.drugbank.com/drugs/DB00324
    ApprovedInvestigational

    A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders.

    Synonyms: (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one, 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dioneMixtures: FLUFORTE-N-LIQUIFILM, FML-neo Oph Sus
  9. Drug

    Crotonaldehyde

    go.drugbank.com/drugs/DB04381
    Experimental

    Synonyms: trans-but-2-enal, 2-Butenal
  10. Drug

    SynKIR-110

    go.drugbank.com/drugs/DB17365
    Investigational

    SynKIR-110 are autologous T cells genetically engineered to express an anti-mesothelin killer immunoglobulin-like receptor-chimeric antigen receptor (KIR-CAR).

    Synonyms: SynKIR-meso CAR-T cells