Bimatoprost is a prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin.
- Mechanism
- Curator reviewed · 4 references
Bimatoprost imitates the effects of prostamides, specifically prostaglandin F2α. Bimatoprost mildly stimulates aqueous humor outflow, relieving elevated intraocular pressure and decreasing the risk of optic nerve damage. It is thought that bimatoprost reduces intraocular pressure (IOP) in humans by causing an increase in outflow of the aqueous humor via the trabecular meshwork and uveoscleral pathways. It achieves the above effects by decreasing tonographic resistance to aqueous humor outflow. Bimatoprost does not affect aqueous humor production.
- Primary indication
- Bimatoprost is used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.Curator reviewed · 4 structured indications
- Formula / weight
- C25H37NO4 · 415.5656 g/mol (avg)
- First approval
- Canada, 2002 · United States, 2001 · European Union, 2016
- Code names
- AGN-192024
- Brand names
Resolves to
AQOKCDNYWBIDND-FTOWTWDKSA-NSMILESCCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1What you can answer from here — as of September 23, 2026
Which drugs share a target with Bimatoprost, and which of those have an active Phase 3 trial?
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