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Displaying results 671 - 680 of 10000 in total
  1. Drug

    GTB-3550

    go.drugbank.com/drugs/DB18494
    Investigational

    GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form

    Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linker
  2. Drug

    Rivabazumab pegol

    go.drugbank.com/drugs/DB17788
    Investigational

    Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.[A259457]

    Synonyms: KB001-A, KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA)
  3. Drug

    Ozanezumab

    go.drugbank.com/drugs/DB12891
    Investigational

    Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.

    Synonyms: IMMUNOGLOBULIN G1, ANTI-(PROTEIN NOGO-A) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER
  4. Drug

    Berberine ursodeoxycholate

    go.drugbank.com/drugs/DB18111
    Investigational

    Synonyms: 9,10-dimethoxy-5,6-dihydro-2H,8H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-8-ylium 3α,7β-dihydroxy-5β-cholan-24-oate, Cholan-24-oic acid, 3,7-dihydroxy-, ion(1-), (3α,5β,7β)-, 5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium (1:1)
  5. Drug

    OTL-102

    go.drugbank.com/drugs/DB18642
    Experimental

    OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. … It is being investigated for the treatment of X-linked chronic granulomatous disease.

    Synonyms: Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene
  6. Drug

    (R)-methylmalonyl-CoA

    go.drugbank.com/drugs/DB04045
    Investigational

    Categories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-RingSynonyms: Methylmalonyl-coenzyme A, (R)-2-Methyl-3-oxopropanoyl-CoA
  7. Drug

    ABT-341

    go.drugbank.com/drugs/DB08044
    Experimental

    ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different). [A39406]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE
  8. Drug

    Gartisertib

    go.drugbank.com/drugs/DB18770
    Investigational

    Synonyms: 2-amino-6-fluoro-n-(5-fluoro-4-(4-((4-(oxetan-3-yl)piperazin-1-yl)carbonyl)-1-piperidyl)-3-pyridyl)pyrazolo(1,5-a)pyrimidine-3-carboxamide, Pyrazolo(1,5-a)pyrimidine-3-carboxamide, 2-amino-6-fluoro-n-(5-fluoro-4-(4-((4-(3-oxetanyl)-1-piperazinyl)carbonyl)-1-piperidinyl)-3-pyridinyl)-
  9. Drug

    TAK-075 Free base

    go.drugbank.com/drugs/DB18268
    Experimental

    Synonyms: Pyrazolo(1,5-a)pyrimidine-3-carboxamide, n-(1-ethyl-1-(4-ethylphenyl)propyl)-4,5,6,7-tetrahydro-2,7,7-trimethyl-5-phenyl-, (5r)-Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Tuvusertib

    go.drugbank.com/drugs/DB18790
    Investigational

    Synonyms: 2-amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide