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Gartisertib

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Data Packages
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Overview

Structure
DrugBank ID
DB18770
Type
Small Molecule
US Approved
NO
Other Approved
NO
Patents
0
Indicated Conditions
0
Clinical Trials
Phase 0
0
Phase 1
20
Phase 2
2
Phase 3
0
Phase 4
0

Identification

Generic Name
Gartisertib
DrugBank Accession Number
DB18770
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 541.564
Monoisotopic: 541.236142156
Chemical Formula
C25H29F2N9O3
Synonyms
  • 2-amino-6-fluoro-n-(5-fluoro-4-(4-((4-(oxetan-3-yl)piperazin-1-yl)carbonyl)-1-piperidyl)-3-pyridyl)pyrazolo(1,5-a)pyrimidine-3-carboxamide
  • Gartisertib
  • Pyrazolo(1,5-a)pyrimidine-3-carboxamide, 2-amino-6-fluoro-n-(5-fluoro-4-(4-((4-(3-oxetanyl)-1-piperazinyl)carbonyl)-1-piperidinyl)-3-pyridinyl)-
External IDs
  • M 4344
  • M-4344
  • M4344
  • VX-803
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available
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Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
7OM98IUD1O
CAS number
1613191-99-3
InChI Key
QAYHKBLKSXWOEO-UHFFFAOYSA-N
InChI
InChI=1S/C25H29F2N9O3/c26-16-9-30-23-20(22(28)32-36(23)12-16)24(37)31-19-11-29-10-18(27)21(19)34-3-1-15(2-4-34)25(38)35-7-5-33(6-8-35)17-13-39-14-17/h9-12,15,17H,1-8,13-14H2,(H2,28,32)(H,31,37)
IUPAC Name
SMILES
NC1=NN2C=C(F)C=NC2=C1C(=O)NC1=CN=CC(F)=C1N1CCC(CC1)C(=O)N1CCN(CC1)C1COC1

References

General References
Not Available
ChemSpider
64866821
BindingDB
412060
ChEMBL
CHEMBL4650286

Clinical Trials

Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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1CompletedTreatmentAdvanced Solid Tumors / Solid Tumors1somestatusstop reasonjust information to hide
1WithdrawnTreatmentRecurrent Ovarian Cancer1somestatusstop reasonjust information to hide
1, 2WithdrawnTreatmentAdvanced Solid Tumors / Breast Cancer1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 19, 2024 18:09 / Updated at June 21, 2024 20:33