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Belumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigational[A236634] It is an inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK), with significantly more selectivity for ROCK2 as compared to ROCK1 (IC<sub>50</sub> 100 nM vs. 3 μM, respectively … [L34749] In the treatment of GVHD, a condition in which donor T-cells begin to attack recipient tissues following allogeneic hematopoeitic stem cell transplantation (HSCT), belumosudil helps to resolve
Estrone sulfate
go.drugbank.com/drugs/DB04574ApprovedEstrone sulfate (as estropipate) is a form of estrogen. … It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelopment of female sexual
Categories: Estrogens, Conjugated (USP), Hormonal Contraceptives for Systemic UseTagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigationalTagraxofusp is a CD123-directed cytotoxin. … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_.
Dihydrocodeine
go.drugbank.com/drugs/DB01551ApprovedIllicitIt is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis … Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.
Mixtures: Panlor SSCategories: Semi-synthetic OpioidsUndecylenic acid
go.drugbank.com/drugs/DB11117ApprovedDue to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.
Mixtures: Hongo Cura RS, Hongo Cura RSCategories: Antifungals for Topical Use, Antifungals for Dermatological UseLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide. … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.
Mixtures: Hyzaar DS, Losartan HCT DSProducts: ZYLTAN 50 (Losartan Potassium Tablets USP 50mg)Methenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedIn salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine). … Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane.
Mixtures: UR N-C Urinary Antiseptic, Urin D/SCategories: Genito Urinary System and Sex Hormones, Antibacterials for Systemic UsePrazepam
go.drugbank.com/drugs/DB01588ApprovedIllicitPrazepam is a benzodiazepine that is used in the treatment of anxiety disorders. It is a schedule IV drug in the U.S.
Methyltestosterone
go.drugbank.com/drugs/DB06710ApprovedInvestigationalMethyltestosterone is a schedule III drug in the US.
Mixtures: Eemt Hs, Covaryx HsCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawnIt was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. … (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942]
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System