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Voriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigationalVoriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. … [A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660]
Categories: Metabolic Side Effects of Drugs and SubstancesProducts: VORICONAZOLO DR REDDY'S, VORICONAZOL AL 50MGNadroparin
go.drugbank.com/drugs/DB08813ApprovedInvestigationalWithdrawnLow molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin. … The amplification of the fibrin clotting cascade is stopped once factors Xa and IIa are inactivated. It is derived from porcine sources and has a mean molecular size of 5000 daltons.
Products: FRAXIPARINE 0.3ML INJ 7,500 IC U AXA, FRAXIPARINE INJECTION 1900 IU AXA/0.2 mLFusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigationalAn antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis.
Mixtures: ACELER-COProducts: FUSIDATO DI SODIO ISDIN, ÁCIDO FUSÍDICO CREMA AL 2%Cefuroxime
go.drugbank.com/drugs/DB01112ApprovedInvestigationalBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Products: Nu-cefuroxime, CEFUROXIM AL 250Neostigmine
go.drugbank.com/drugs/DB01400ApprovedInvestigationalVet approvedA cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.
Products: NEOSTIGMINA METILSULFATO SOLUCION INYECTABLE DE 0.5 MG / 1 ML.Piracetam
go.drugbank.com/drugs/DB09210ApprovedWithdrawnIt shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). … In the UK, piracetam is prescribed mainly for myoclonus, but is used off-label for other conditions such as learning difficulties in children, memory loss or other cognitive defects in the elderly, and
Categories: Compounds used in a research, industrial, or household settingProducts: PIRACETAM AL 800, PIRACETAM AL 1200Bismuth subsalicylate
go.drugbank.com/drugs/DB01294ApprovedVet approved[L32318] Bismuth subsalicylate is a component of HELIDAC Therapy (bismuth subsalicylate, [metronidazole], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ … [A230728] It is an active ingredient found in Pepto-Bismol, a common over-the-counter medication that is used to temporarily treat discomforts of the stomach and gastrointestinal tract.
Products: Kola-Pectin DS, Dg Health Stomach Relief Maximum StrengthMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[A180322] This inhibition leads to suppression of inflammation as well as prevention of cell division. … [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients
Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: TRIXILEM RU, TRIXILEM®RU SOLUCION INYECTABLETeriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalTeriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. … The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.
Products: TERIFLUNOMIDE DR. REDDY'SAnagrelide
go.drugbank.com/drugs/DB00261ApprovedInvestigational[L14153] It is an oral imidazoquinazoline that was first approved for use in the US in 1997.[A214274] It appears to carry a better response rate than other thrombocythemia treatments (e.g. … Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: ANAGRELID AL 0.5MG HKP