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Terazosin
go.drugbank.com/drugs/DB01162ApprovedInvestigationalTerazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label][A176831].
Categories: P-glycoprotein inhibitors, Antihypertensive Agents Indicated for HypertensionProducts: FLOTRIN 10MG MAXGalsulfase
go.drugbank.com/drugs/DB01279ApprovedInvestigationalThe recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular … Post-translational modification of Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family
Products: Naglazyme Concentrated Solution for Intravenous Infusion 1mg/1mlNemolizumab
go.drugbank.com/drugs/DB15252ApprovedInvestigationalNemolizumab is a humanized monoclonal modified immunoglobulin 2 (IgG2) antibody directed against interleukin-31 receptor alpha (IL-31RA),[L51159] which is an endogenous cytokine implicated in the pathophysiology … [A264274] It was later approved by the FDA on August 13, 2024, for the treatment of prurigo nodularis.[L51169]
Categories: Agents for Dermatitis, Excluding Corticosteroids, Interleukin-31 Receptor alpha AntagonistSynonyms: Immunoglobulin G2, anti-(interleukin 31 receptor A) (human-Mus musculus monoclonal CIM331 γ-chain), disulfide with human-Mus musculus monoclonal CIM331 κ-chain, dimer, immunoglobulin G2-kappa, anti-[Homo sapiens IL31RA (interleukin 31 receptor subunit alpha)], humanized monoclonal antibody gamma2 heavy chain (1-445) [humanized VH (Homo sapiens IGHV1-2*02 (83.70%) -(IGHDTiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigational[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than [ipratropium].
Mixtures: Spiolto Respimat 2,5 Mikrogramm/2,5 Mikrogramm Lösung zur Inhalation, Yanimo Respimat 2,5 Mikrogramm/2,5 Mikrogramm Lösung zur InhalationCategories: Drugs for Obstructive Airway Diseases, Cytochrome P-450 SubstratesOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigational[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and … [A183782,L8648] This drug relieves undesirable urinary symptoms, increasing the quality of life for patients affected by OAB. It is often used as first-line therapy for OAB.[A185990]
Categories: Drugs for Urinary Frequency and Incontinence, Cytochrome P-450 SubstratesProducts: Oxytrol For Women, Oxytrol for WomenTriclosan
go.drugbank.com/drugs/DB08604ApprovedAn aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Mixtures: Germa TanProducts: Bio-main San, Anti-Bacterial Gentle Foaming Hand Noir for MenFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout who have an inadequate response or intolerance to [allopurinol … Febuxostat works by inhibiting the activity of an enzyme that is responsible for the synthesis of uric acid, thereby reducing serum uric acid levels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Mar-febuxostatBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigationalBisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Categories: Drugs for ConstipationProducts: P Lax Dr, Laxative for WomenLecithin, soybean
go.drugbank.com/drugs/DB14161InvestigationalThe emulsifying and surfactant properties are useful in food additives and for forming organogels (gels).
Mixtures: BEAUTIFUL CONTRACT - Slimming contract -Hui Ju Sheng Enterprise Corporation Ltd., GNC PP AA FormulaProducts: Essentiale MAX 600mg CapsuleCholestyramine
go.drugbank.com/drugs/DB01432ApprovedInvestigationalCholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaProducts: PHL-cholestyramine Powder for Suspension 400gm/can, VASOSAN P BTL