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Hydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigationalOriginally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hyperte...
Products: Apresoline Tablets, 10mg, Apresoline Tablets, 25mgPrimaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigational(From Martindale, The Extra Pharmacopeia, 30th ed, p404) … It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria.
Products: PRIMAQUINE TABLETS 15 MG, PHARMANIAGA PRIMAQUINE TABLET 7.5MGEnzalutamide
go.drugbank.com/drugs/DB08899ApprovedInvestigational[A252667,A252642] Due to a favorable pharmacological profile, a phase 1 study of enzalutamide was initiated in July 2007. … [A252667] Second-generation such as enzalutamide is more efficacious due to a higher affinity to AR and no partial agonist activity compared to bicalutamide.
Products: XTANDI 80 MG TABLETAS, XTANDI® 40MG TABLETASIsoconazole
go.drugbank.com/drugs/DB08943ApprovedIsoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Products: NITRATO DE ISOCONAZOL CREMA1%, E-MIZOLCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalD<sub>3</sub>. … Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin
Synonyms: 1α,25-dihydroxyvitamin D3, 1-alpha-25-Dihydroxyvitamin D3Categories: Vitamin D and AnaloguesZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedStudies show that zinc may be better absorbed in humans in the gluconate form [A32412], [L2105], however, results from other studies may vary.
Mixtures: Citrate De Calcium Plus Vitamine D Et Zinc, Adeks TabletsProducts: Zinc Tablets 50mg, Zinc (gluconate) 10 Mg TabletsDesipramine
go.drugbank.com/drugs/DB01151ApprovedThe antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … Desipramine may be used to treat depression, neuropathic pain (unlabeled use), agitation and insomnia (unlabeled use) and attention-deficit hyperactivity disorder (unlabeled use).
Products: Penta-desipramine Tablets, Dom-desipramine Tablets - 50mgDaclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnIt is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . … Binding to the N-terminus of the D1 domain of NS5A prevents its interaction with host cell proteins and membranes required for virion replication complex assembly.
Products: DASVIR 30 (DACLATASVIR TABLETS 30 MG), DASVIR 60 (DACLATASVIR TABLETS 60 MG)Hydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigationalHydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely b...
Mixtures: DOVIR® TABLETAS, DOVIR ® TABLETASProducts: Hycodan TabletsIdebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalDue to its biochemical mode of action, it's thought that idebenone may re-activate viable-but-inactive retinal ganglion cells (RGCs) in LHON patients [L885]. … Due to its ability to reduce oxidative damage and improve ATP production, idebenone was originally investigated for its potential use in Alzheimer's Disease and other cognitivie disorders [A19769].
Mixtures: EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET, EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLETProducts: KEW TABLETAS, IDEBEX 45 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET