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Displaying results 6821 - 6830 of 10000 in total
  1. Drug

    Seliciclib

    go.drugbank.com/drugs/DB06195
    Investigational

    R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated … Developed by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation

  2. Drug

    Egaptivon pegol

    go.drugbank.com/drugs/DB05202
    Investigational

    Egaptivon pegol, formerly known as ARC1779, is a therapeutic aptamer antagonist of the A1 domain of von Willebrand Factor (vWF), the ligand for receptor glycoprotein 1b on platelets. … [A3290, A259053] Egaptivon pegol is a therapeutic oligonucleotide ("aptamer") which blocks the binding of the A1 domain of vWF to the platelet GPIb receptor, thereby modulating platelet adhesion, activation

  3. Drug

    Farnesol

    go.drugbank.com/drugs/DB02509
    Investigational

    It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. … A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose.

  4. Drug

    Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15731
    Investigational

    Enrichment of CD362 expression in MSCs is being investigated for its role in immune modulation of injured tissue. … ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord.

  5. Drug

    Zavacorilant

    go.drugbank.com/drugs/DB21509
    Investigational

    Zavacorilant is a small molecule drug. The usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal). … Zavacorilant is under investigation in clinical trial NCT04672512 (Single and Multiple Ascending Dose Study of CORT125329 in Healthy Participants).

  6. Drug

    Xiliertinib

    go.drugbank.com/drugs/DB21453
    Investigational

    Xiliertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Xiliertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Xiliertinib is under investigation in clinical trial NCT02601274 (Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor). Xiliertinib has a monoisotopic molecular weight of 442.21 Da.

  7. Drug

    Paltimatrectinib

    go.drugbank.com/drugs/DB21588
    Investigational

    Paltimatrectinib is a small molecule drug. The usage of the INN stem '-trectinib' in the name indicates that Paltimatrectinib is a tropomyosin receptor kinase (TRK) inhibitor. … Paltimatrectinib is under investigation in clinical trial NCT04901806 (Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors).

  8. Drug

    Tirfipiravir

    go.drugbank.com/drugs/DB21648
    Experimental

    Tirfipiravir is a small molecule drug. The usage of the INN stem '-vir' in the name indicates that Tirfipiravir is a antiviral. Tirfipiravir has a monoisotopic molecular weight of 355.1 Da.

  9. Drug

    Clometherone

    go.drugbank.com/drugs/DB19465
    Experimental

    Clometherone is a small molecule drug. The usage of the INN stem '-terone' in the name indicates that Clometherone is a antiandrogen. Clometherone has a monoisotopic molecular weight of 362.2 Da.

  10. Drug

    Derquantel

    go.drugbank.com/drugs/DB19531
    Experimental

    Derquantel is a small molecule drug. The usage of the INN stem '-antel' in the name indicates that Derquantel is a anthelminthic. Derquantel has a monoisotopic molecular weight of 479.28 Da.