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Navarixin
go.drugbank.com/drugs/DB11711InvestigationalNavarixin has been investigated for the treatment of Asthma.
Sarcosine
go.drugbank.com/drugs/DB12519InvestigationalSarcosine has been investigated for the treatment of Schizophrenia.
TAS-102
go.drugbank.com/drugs/DB08937InvestigationalIt is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine. Trifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis. … TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer.
Seliciclib
go.drugbank.com/drugs/DB06195InvestigationalDeveloped by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation … R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated
Candoxatrilat
go.drugbank.com/drugs/DB11623ExperimentalA dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy … A potent inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug in the treatment of chronic heart failure.
Icenticaftor
go.drugbank.com/drugs/DB21466InvestigationalThe usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.
Rezivertinib
go.drugbank.com/drugs/DB21471InvestigationalThe usage of the INN stem '-ertinib' in the name indicates that Rezivertinib is a epidermal growth factor receptor (EGFR) inhibitor.
Tuxobertinib
go.drugbank.com/drugs/DB21508InvestigationalThe usage of the INN stem '-ertinib' in the name indicates that Tuxobertinib is a epidermal growth factor receptor (EGFR) inhibitor.
Fipravirimat
go.drugbank.com/drugs/DB21578InvestigationalThe usage of the INN stem '-virimat' in the name indicates that Fipravirimat is a antiviral, disruptor of viral maturation.
Opnurasib
go.drugbank.com/drugs/DB21583InvestigationalThe usage of the INN stem '-rasib' in the name indicates that Opnurasib is a Ras protein inhibitor.