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Volenrelaxin
go.drugbank.com/drugs/DB21750InvestigationalVolenrelaxin is under investigation in clinical trial NCT06598631 (Efficacy and Safety of Volenrelaxin in Adults With Chronic Kidney Disease).
VPM1002
go.drugbank.com/drugs/DB15801InvestigationalThis recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults through post-exposure immunization. … Because Hly is only active at an acidic pH, similar to listeriolysin O, the deletion of urease C was also beneficial for Hly to have optimal bioactivity in the phagosome.
NB-001
go.drugbank.com/drugs/DB12716InvestigationalNB-001 has been investigated for the treatment of Recurrent Herpes Labialis.
GALE-301
go.drugbank.com/drugs/DB17262InvestigationalGALE-301 is an investigational cancer immunotherapy. … It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune adjuvant, granulocyte macrophage-colony stimulating factor (GM-CSF).[A254696,L44166,L44171]
Nomacopan
go.drugbank.com/drugs/DB14991InvestigationalNomacopan is under investigation in clinical trial NCT03427060 (Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms).
Isuzinaxib
go.drugbank.com/drugs/DB19109InvestigationalIsuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).
Inlexisertib
go.drugbank.com/drugs/DB21713InvestigationalInlexisertib is under investigation in clinical trial NCT05957367 (A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies). … The usage of the INN stem '-sertib' in the name indicates that Inlexisertib is a serine/threonine kinase inhibitor.
PF-04856884
go.drugbank.com/drugs/DB17550Investigational[A257291] It is under investigation in clinical trial NCT01441414 (PF-04856884 (CVX-060) in Combination With Axitinib in Patients With Previously Treated Metastatic Renal Cell Carcinoma).
Melrilimab
go.drugbank.com/drugs/DB16373InvestigationalMelrilimab is under investigation in clinical trial NCT03207243 (Efficacy and Safety Study of GSK3772847 in Subjects With Moderately Severe Asthma).
ANC-501
go.drugbank.com/drugs/DB18907InvestigationalANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).
Synonyms: 3-(3-Chlorophenyl)-1,5-dihydro-N-(1-methylethyl)-1-[4-[2-(4-morpholinyl)ethyl]phenyl]-5-oxo-4H-1,2,4-triazole-4-acetamide