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Displaying results 6871 - 6880 of 10000 in total
  1. Drug

    Pentamustine

    go.drugbank.com/drugs/DB21291
    Experimental

    Pentamustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Pentamustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. … Pentamustine has a monoisotopic molecular weight of 221.09 Da.

  2. Drug

    Izilendustat

    go.drugbank.com/drugs/DB21532
    Experimental

    Izilendustat is a small molecule drug. The usage of the INN stem '-dustat' in the name indicates that Izilendustat is a hypoxia inducible factor (HIF) prolyl hydroxylase inhibitor. … Izilendustat has a monoisotopic molecular weight of 433.18 Da.

  3. Drug

    Civorebrutinib

    go.drugbank.com/drugs/DB21641
    Experimental

    Civorebrutinib is a small molecule drug. The usage of the INN stem '-brutinib' in the name indicates that Civorebrutinib is a agammaglobulinaemia tyrosine kinase (Bruton tyrosine kinase) inhibitor. … Civorebrutinib has a monoisotopic molecular weight of 463.15 Da.

  4. Drug

    Pipazethate

    go.drugbank.com/drugs/DB08796
    Investigational

    A non-narcotic oral antitussive agent.

    Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Norclozapine

    go.drugbank.com/drugs/DB05766
    Investigational

    ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia. … It combines an atypical antipsychotic efficacy profile with the added potential benefit of enhanced cognition, thereby addressing one of the major challenges in treating schizophrenia today.

    Categories: Heterocyclic Compounds, 3-RingSynonyms: N-Desmethylclozapine
  6. Drug

    PMI-001

    go.drugbank.com/drugs/DB05730
    Experimental

    It is an extract of the roots of an undisclosed perennial shrub which interferes with the production of IL-2 and COX-2 proteins, for the potential treatment of autoimmune diseases, such as rheumatoid arthritis … PMI-001 is a stand-alone, disease-modifying, anti-rheumatic drug (DMARD) being developed by Phytomedics Inc.

  7. Drug

    Azosemide

    go.drugbank.com/drugs/DB08961
    Investigational

    Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 2-chloro-5-(1H-tetrazol-5-yl)-N4-2-thenylsulfanilamide, 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazole
  8. Drug

    OAV201

    go.drugbank.com/drugs/DB17842
    Experimental

    OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter … It was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical trials was halted.[L46661]

  9. Drug

    1alpha,24S-Dihydroxyvitamin D2

    go.drugbank.com/drugs/DB06117
    Experimental

    LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. … It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol, but much lower toxicity.

    Categories: Vitamin D and Analogues
  10. Drug

    Evifacotrep

    go.drugbank.com/drugs/DB21510
    Investigational

    Evifacotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Evifacotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist. … Evifacotrep has a monoisotopic molecular weight of 441.06 Da.