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Displaying results 6871 - 6880 of 10000 in total
  1. Drug

    Dactinomycin

    go.drugbank.com/drugs/DB00970
    ApprovedInvestigational

    A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release.

    Synonyms: ACTINOMYCIN I1, Actinomycin IV
  2. Drug

    Indopan

    go.drugbank.com/drugs/DB01446
    ExperimentalIllicit

    It was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United states. … Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar.

    Synonyms: 1-(1H-Indol-3-yl)-2-propanamine, DL-3-(2-Aminopropyl)indole
  3. Drug

    5-methoxy-N,N-dimethyltryptamine

    go.drugbank.com/drugs/DB14010
    IllicitInvestigational

    It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. … This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South America in religious and spiritual rituals.

  4. Drug

    Eperisone

    go.drugbank.com/drugs/DB08992
    Investigational

    It is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh. … Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and

  5. Drug

    Norfloxacin succinil

    go.drugbank.com/drugs/DB20858
    Experimental

    Norfloxacin succinil is a small molecule drug. The usage of the INN stem '-nil' in the name indicates that Norfloxacin succinil is a benzodiazepine receptor antagonist/agonist. … The usage of the INN stem '-oxacin' in the name indicates that Norfloxacin succinil is a nalidixic acid derivative antibacterial. Norfloxacin succinil has a monoisotopic molecular weight of 419.15 Da.

  6. Drug

    Bicuculline

    go.drugbank.com/drugs/DB11562
    Experimental

    It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors.

  7. Drug

    Ulixertinib

    go.drugbank.com/drugs/DB13930
    Investigational

    It is currently in clinical trials for the treatment of a wide range of tumors. … Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474].

  8. Drug

    Ontuxizumab

    go.drugbank.com/drugs/DB16270
    Investigational

    It is under investigation in clinical trial NCT01574716 (Sarcoma Study of Morab-004 Utilization: Research and Clinical Evaluation). … Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 (TEM-1).

  9. Drug

    Melogliptin

    go.drugbank.com/drugs/DB20789
    Experimental

    Melogliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Melogliptin is a dipeptidyl aminopeptidase-IV inhibitor.

  10. Drug

    Garvagliptin

    go.drugbank.com/drugs/DB21280
    Experimental

    Garvagliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Garvagliptin is a dipeptidyl aminopeptidase-IV inhibitor.