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Displaying results 6871 - 6880 of 10000 in total
  1. Drug

    Lepzacitinib

    go.drugbank.com/drugs/DB21646
    Investigational

    Lepzacitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Lepzacitinib is a Janus kinase inhibitor. … Lepzacitinib is under investigation in clinical trial NCT05432596 (Study of ATI-1777 in Patients 12 to 65 Years Old With Mild to Severe Atopic Dermatitis).

  2. Drug

    Luvometinib

    go.drugbank.com/drugs/DB21696
    Investigational

    Luvometinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Luvometinib is a tyrosine kinase inhibitor. … Luvometinib is under investigation in clinical trial NCT07004075 (FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration).

  3. Drug

    Pebezertinib

    go.drugbank.com/drugs/DB21705
    Investigational

    Pebezertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Pebezertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Pebezertinib is under investigation in clinical trial NCT05241873 ((Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations).

  4. Drug

    Navamepent

    go.drugbank.com/drugs/DB21096
    Investigational

    Navamepent is under investigation in clinical trial NCT02329743 (Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery). … Navamepent has a monoisotopic molecular weight of 304.17 Da.

  5. Drug

    Aderbasib

    go.drugbank.com/drugs/DB21288
    Investigational

    Aderbasib is under investigation in clinical trial NCT01254136 (Safety and Efficacy of INCB007839 With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast Cancer). … Aderbasib has a monoisotopic molecular weight of 416.21 Da.

  6. Drug

    Irampanel

    go.drugbank.com/drugs/DB21123
    Investigational

    Irampanel is under investigation in clinical trial NCT02222961 (Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers). … Irampanel has a monoisotopic molecular weight of 309.15 Da.

  7. Drug

    AP5346

    go.drugbank.com/drugs/DB04992
    Investigational

    AP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer.

  8. Drug

    Crobenetine

    go.drugbank.com/drugs/DB21095
    Investigational

    Crobenetine is under investigation in clinical trial NCT02273466 (Pharmacokinetics of Oral Desipramine With and Without Concomitant Administration of Crobenetine Infusion in Healthy Male Subjects). … Crobenetine has a monoisotopic molecular weight of 379.25 Da.

  9. Drug

    Dalzanemdor

    go.drugbank.com/drugs/DB21549
    Investigational

    Dalzanemdor is under investigation in clinical trial NCT05655520 (A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease). … Dalzanemdor has a monoisotopic molecular weight of 456.32 Da.

  10. Drug

    anti-OX40 antibody BMS 986178

    go.drugbank.com/drugs/DB15773
    Investigational

    A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.