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Epithelial discoidin domain-containing receptor 1
go.drugbank.com/bio_entities/BE0001124TargetHumansPromotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11 … , survival and cell proliferation.
Synonyms: CAK, Tyrosine-protein kinase CAKAGA2115
go.drugbank.com/drugs/DB17840InvestigationalAGA2115 is a humanized bispecific antibody neutralizing both sclerostin and Dickkopf-1. … Developed by Angitia Biopharmaceuticals, AGA2115 is being investigated for the treatment of osteogenesis imperfect.[L46646]
SMART101
go.drugbank.com/drugs/DB18370InvestigationalSMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.
ALLO-605
go.drugbank.com/drugs/DB18641InvestigationalALLO-605 is an allogeneic turbo chimeric antigen receptor (Turbocar) T Cell therapy targeting B Cell maturation antigen (BCMA).
RC88
go.drugbank.com/drugs/DB18697ExperimentalRC88 is an antibody-drug conjugate comprising a humanized anti-mesothelin monoclonal antibody conjugated to monomethyl auristatin E (MMAE).
E-2012
go.drugbank.com/drugs/DB05171ExperimentalE-2012 is a gamma secretase modulator that is being evaluated as a potential new treatment for Alzheimer's disease.
Categories: Gamma Secretase Inhibitors and ModulatorsTanaproget
go.drugbank.com/drugs/DB04787ExperimentalTanaproget (NSP-989) is an investigational non-steroidal progestin. … An analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging of the PR in positron emission tomography.
Licofelone
go.drugbank.com/drugs/DB04725ExperimentalDeveloped by the German pharmaceutical company, Merckle GmbH, together with EuroAlliance partners Alfa Wassermann and Lacer, licofelone (ML3000) is a dual COX/LOX inhibitor and the first member of this … new class of analgesic and anti-inflammatory drugs.
BACTEK-R
go.drugbank.com/drugs/DB16526InvestigationalMV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that are involved in upper and lower respiratory infections. … These include streptococcus pneumoniae and staphylococcus aureus.