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Lomedeucitinib
go.drugbank.com/drugs/DB21649InvestigationalLomedeucitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Lomedeucitinib is a Janus kinase inhibitor. … Lomedeucitinib is under investigation in clinical trial NCT05730725 (A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe Psoriasis).
Bimokalner
go.drugbank.com/drugs/DB21717InvestigationalBimokalner is a small molecule drug. The usage of the INN stem '-kalner' in the name indicates that Bimokalner is a opener of calcium-activated (maxi-K) K+-channel. … Bimokalner is under investigation in clinical trial NCT06521190 (ACOU085 for Hearing Loss Prevention in Testicular Cancer Patients Receiving Cisplatin).
Alpibectir
go.drugbank.com/drugs/DB21561InvestigationalAlpibectir is under investigation in clinical trial NCT06748937 (A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide). … Alpibectir has a monoisotopic molecular weight of 332.1 Da.
Ceperognastat
go.drugbank.com/drugs/DB21591InvestigationalCeperognastat is under investigation in clinical trial NCT05063539 (A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease). … Ceperognastat has a monoisotopic molecular weight of 383.14 Da.
Ranosidenib
go.drugbank.com/drugs/DB21727InvestigationalRanosidenib is a small molecule drug. Ranosidenib is under investigation in clinical trial NCT06387069 (A Study to Evaluate HMPL-306 in Patients With IDH1- and IDH2-mutated Acute Myeloid Leukemia). … Ranosidenib has a monoisotopic molecular weight of 453.12 Da.
Sonpiretigene isteparvovec
go.drugbank.com/drugs/DB17844InvestigationalSonpiretigene isteparvovec is an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic therapy. … Developed by Nanoscope Therapeutics, it is being investigated for vision restoration in advanced retinitis pigmentosa (RP).
Antithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. … Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.
NOP-1A
go.drugbank.com/drugs/DB15208InvestigationalNOP-1A is under investigation in clinical trial NCT01198197 (PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A).
Synonyms: NOP-1AConteltinib
go.drugbank.com/drugs/DB21262InvestigationalConteltinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Conteltinib is a tyrosine kinase inhibitor. … Conteltinib is under investigation in clinical trial NCT06970132 (Study of SY-5933 Plus CT-707 in Advanced Solid Tumors With KRAS p.G12C Mutation).