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Displaying results 6881 - 6890 of 10000 in total
  1. Drug

    Azosemide

    go.drugbank.com/drugs/DB08961
    Investigational

    Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.

    Synonyms: 2-chloro-5-(1H-tetrazol-5-yl)-N4-2-thenylsulfanilamide, 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazoleCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  2. Drug

    PMI-001

    go.drugbank.com/drugs/DB05730
    Experimental

    It is an extract of the roots of an undisclosed perennial shrub which interferes with the production of IL-2 and COX-2 proteins, for the potential treatment of autoimmune diseases, such as rheumatoid arthritis … PMI-001 is a stand-alone, disease-modifying, anti-rheumatic drug (DMARD) being developed by Phytomedics Inc.

  3. Drug

    Bevurogant

    go.drugbank.com/drugs/DB21507
    Experimental

    The usage of the INN stem '-rogant' in the name indicates that Bevurogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist. … Bevurogant is a small molecule drug.

  4. Drug

    Selenocysteine

    go.drugbank.com/drugs/DB02345
    Investigational

    A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. … The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid. [PubChem]

    Synonyms: 3-selenyl-L-alanine, L-selenocysteineMixtures: Dialyvite Supreme D
  5. Drug

    Izumerogant

    go.drugbank.com/drugs/DB21604
    Experimental

    The usage of the INN stem '-rogant' in the name indicates that Izumerogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist. … Izumerogant is a small molecule drug.

  6. Drug

    AZD 3355

    go.drugbank.com/drugs/DB05404
    Investigational

    AZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. It is developed by AstraZeneca and is currently in phase I/II trials.

    Categories: GABA-A Receptor Agonists
  7. Drug

    Endostar

    go.drugbank.com/drugs/DB11727
    Investigational

    Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.

    Synonyms: Endostatin, N-terminal-MGGSHHHHH, N-TERMINAL-MGGSHHHHH-ENDOSTATIN
  8. Drug

    Phytic acid

    go.drugbank.com/drugs/DB14981
    Investigational

    Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).

    Synonyms: D-myo-Inositol 1,2,3,4,5,6-hexakisphosphate
  9. Drug

    Monalizumab

    go.drugbank.com/drugs/DB12824
    Investigational

    Monalizumab has been used in trials studying the treatment of Gynecologic Cancer, Chronic Lymphocytic Leukemia, and Squamous Cell Carcinoma of the Oral Cavity.

  10. Drug

    GTI-2501

    go.drugbank.com/drugs/DB05406
    Experimental

    The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer. … GTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial.