Search
Lactobacillus paracasei
go.drugbank.com/drugs/DB16551InvestigationalSynonyms: L. paracaseiMixtures: RisaQuad-2Tetramisole
go.drugbank.com/drugs/DB16561InvestigationalTetramisole is an anthelmintic agent.[A275223]
Categories: Heterocyclic Compounds, 1-RingFuraltadone
go.drugbank.com/drugs/DB16567InvestigationalSynonyms: (±)-5-(MORPHOLINOMETHYL)-3-((5-NITROFURFURYLIDENE)AMINO)-2-OXAZOLIDINONECategories: Heterocyclic Compounds, 1-RingPoliomyelitis virus type 1 (live, attenuated)
go.drugbank.com/drugs/DB16578InvestigationalMixtures: ไบวาเลนท์ โอรัล โปลิโอ วัคซีน ทัยป์ 1 และ 3, วัคซีนป้องกันโปลิโอสองสายพันธุ์ (สายพันธุ์ 1 และ 3) ชนิดรับประทานSynonyms: Poliomyelitis virus type 1, LS - c2ab strain, Poliomyelitis virus type 1 (live, attenuated)Afimetoran
go.drugbank.com/drugs/DB16580InvestigationalAfimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8. … [L32018, L32023] It is also is under investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male
Darvadstrocel
go.drugbank.com/drugs/DB16581ApprovedInvestigationalWithdrawnPerianal fistula is a common manifestation of Crohn’s disease and is often difficult to manage, as it may be associated with complex presentations and symptoms. … Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted from the subdermal adipose tissue of healthy donors via liposuction.
Almonertinib
go.drugbank.com/drugs/DB16640ApprovedInvestigationalAlmonertinib is a third-generation EGFR tyrosine kinase inhibitor targeting EGFR-sensitizing and T790M resistance mutations. … [A231859, A231864, A231869] Unlike other third-generation EGFR TKIs, almonertinib is a pyrimidine-based drug that forms a covalent bond to the binding site of the EGFR tyrosine kinase domain.
Categories: MATE 1 Inhibitors, P-glycoprotein inhibitorsSynonyms: 2-Propenamide, N-[5-[[4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-, N-[5-[[4-(1-Cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-2-propenamideSugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigationalit to have a better safety profile through avoiding unwanted attack of T-cells. … Sugemalimab is a fully human, full-length anti-programmed death-ligand 1 (PD-L1) monoclonal antibody (of the IgG4 isotype) discovered by CStone Pharmaceuticals.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsDonanemab
go.drugbank.com/drugs/DB16647ApprovedInvestigationalDonanemab is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against insoluble N-truncated pyroglutamate amyloid beta (Aβ), [L50978] which is found in the brain amyloid plaques that … [A232214] On July 2, 2024, donanemab was approved by the FDA for the treatment of AD in patients with mild cognitive impairment or dementia symptoms.
Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS APP (AMYLOID BETA A4 PRECURSOR PROTEIN) A BETA 3-PYROGLUTAMYL PEPTIDES, A.BETA. 3 (3-X)), HUMANIZED MONOCLONAL ANTIBODYGAMMA1 HEAVY CHAIN HUMANIZED (1-444) (, Immunoglobulin G1, anti-(human pyroglutamyl Aβ (3-x) peptide)(human clone LY3002813 γ1-chain), disulfide with human clone LY3002813 κ-chain, dimer