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All 12,340
Drugs 12,337
Targets 3
Indications 0
Pathways 0

Displaying results 6891 - 6900 of 10000 in total

Drug
Capmatinib
go.drugbank.com/drugs/DB11791
ApprovedInvestigational
[A199122] This co-occurrence has made c-Met a desirable target in the treatment of NSCLC. … Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades
Categories: MATE 2-K Inhibitors, MATE 1 Inhibitors
Drug
Bictegravir
go.drugbank.com/drugs/DB11799
ApprovedInvestigational
It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.[L43677] … Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection.
Categories: MATE 1 Inhibitors, Cytochrome P-450 Substrates
Drug
Pridopidine
go.drugbank.com/drugs/DB11947
Investigational
Pridopidine has been used in trials studying the treatment of Huntington's Disease.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Ilaprazole
go.drugbank.com/drugs/DB11964
Investigational
Ilaprazole has been investigated in Helicobacter Infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 7 ADET
Drug
Elamipretide
go.drugbank.com/drugs/DB11981
ApprovedInvestigational
[A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … Elamipretide is a mitochondrial cardiolipin binder being investigated for diseases involving mitochondrial dysfunction.
Categories: MATE 1 Inhibitors
Drug
Nirogacestat
go.drugbank.com/drugs/DB12005
ApprovedInvestigational
Nirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors. … DeFi trial, where a confirmed objective response rate was observed to be 41% compared to 8% with the placebo.
Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
Drug
Ozagrel
go.drugbank.com/drugs/DB12017
Investigational
Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.
Categories: Thromboxane-A Synthase, antagonists & inhibitors
Drug
Evatanepag
go.drugbank.com/drugs/DB12022
Investigational
Evatanepag has been used in trials studying the treatment of Tibial Fractures.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Sarecycline
go.drugbank.com/drugs/DB12035
ApprovedInvestigational
s Seysara (sarecylcine) as a new first in class narrow spectrum tetracycline derived oral antibiotic for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients … Subsequently, while a number of first line tetracycline therapies like doxycycline and minocycline do exist for treating acne vulgaris, sarecycline presents a new and innovative therapy choice because
Categories: P-glycoprotein inhibitors
Drug
Crenigacestat
go.drugbank.com/drugs/DB12050
Investigational
Crenigacestat has been used in trials studying the treatment and basic science of LYMPHOMA, Neoplasms, Solid Tumor, COLON CANCER, and BREAST CANCER, among others.
Categories: Heterocyclic Compounds, 2-Ring