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Displaying results 6891 - 6900 of 9333 in total
  1. Drug

    Vamifeport

    go.drugbank.com/drugs/DB17692
    Investigational

    Vamifeport is being investigated for the treatment of beta-thalassemia.

  2. Drug

    Zavacorilant

    go.drugbank.com/drugs/DB21509
    Investigational

    The usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal).

  3. Drug

    Neladalkib

    go.drugbank.com/drugs/DB21712
    Investigational

    The usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor.

  4. Drug

    Fenspiride

    go.drugbank.com/drugs/DB08979
    Investigational

    It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis … Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.

  5. Drug

    Leukotriene C4

    go.drugbank.com/drugs/DB08855
    Experimental

    The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. … It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)

    Synonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycine
  6. Drug

    Xiliertinib

    go.drugbank.com/drugs/DB21453
    Investigational

    The usage of the INN stem '-ertinib' in the name indicates that Xiliertinib is a epidermal growth factor receptor (EGFR) inhibitor.

  7. Drug

    Paltimatrectinib

    go.drugbank.com/drugs/DB21588
    Investigational

    The usage of the INN stem '-trectinib' in the name indicates that Paltimatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.

  8. Drug

    OBE101

    go.drugbank.com/drugs/DB05080
    Experimental

    It is a new formulation that is based on the vertigo medication, Betahistine. … Obecure is repurposing betahistine, which is an H1 receptor agonist and partial H3 receptor antagonist for the treatment of obese individuals and for other weight management indications.

  9. Drug

    ISIS 113715

    go.drugbank.com/drugs/DB05506
    Investigational

    ISIS 113715 is our second-generation antisense inhibitor of protein tyrosine phosphatase 1b, or PTP‑1b, for the treatment of type 2 diabetes.

  10. Drug

    CIGB-258 peptide

    go.drugbank.com/drugs/DB15809
    Experimental

    As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens … CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant.