DB08855ExperimentalSmall molecule
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle.
- Mechanism
- Curator reviewed
Pharmacologically active on Cysteinyl leukotriene receptor 1 and Cysteinyl leukotriene receptor 2
- Formula / weight
- C30H47N3O9S · 625.774 g/mol (avg)
- Also known as
- LTC (sub 4) · LTC4
Resolves to
Structure
InChIKey
GWNVDXQDILPJIG-NXOLIXFESA-NSMILESCCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=OTransporters
What you can answer from here — as of April 02, 2025
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
2TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Leukotriene C4, and which of those have an active Phase 3 trial?
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