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Rodatristat
go.drugbank.com/drugs/DB18478ExperimentalSynonyms: (3s)-8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)-4-pyrimidinyl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid, (3s)-8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylic acidCategories: Heterocyclic Compounds, 1-RingHeparan-N-sulfatase (human, recombinant)
go.drugbank.com/drugs/DB18483InvestigationalRecombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis type IIIA.
Synonyms: Recombinant human heparan-N-sulfatase, Heparan-N-sulfatase (human, recombinant)ALT-P1
go.drugbank.com/drugs/DB18485InvestigationalALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
KT-253
go.drugbank.com/drugs/DB18487InvestigationalKT-253 is a selective heterobifunctional small molecule degrader of mouse double minute 2 (MDM2).
DMP-777
go.drugbank.com/drugs/DB18488ExperimentalDMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL)CARBONYL)PHENOXY)-4-OXO-, (2S)-LTI-03
go.drugbank.com/drugs/DB18491InvestigationalLTI-03 is a caveolin-1 Scaffolding Domain 7-Mer
Synonyms: L-threonine, l-phenylalanyl-l-threonyl-l-threonyl-l-phenylalanyl-l-threonyl-l-valyl-STP-707
go.drugbank.com/drugs/DB18499InvestigationalSTP-707 is a small interfering RNA (siRNA) targeting TGF-Beta1 and COX-2 mRNA.
ISP-001
go.drugbank.com/drugs/DB18501InvestigationalISP-001 consists of sleeping beauty transposon-engineered autologous plasmablasts for expression and delivery of alpha-L-iduronidase.
ACTX-401
go.drugbank.com/drugs/DB18504ExperimentalACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human immunoglobulin u-binding protein 2 cDNA.
EA-2353
go.drugbank.com/drugs/DB18506InvestigationalEA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway.