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SGS518

SGS518, a novel antagonist for the 5HT6 subtype of the serotonin receptor, is being developed as a treatment for Cognitive Impairment Associated with Schizophrenia (CIAS).

2,3-Dimercapto-1-propanesulfonic acid

t-Butylhydroquinone

Hesperetin

Hesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges.

MDX-1379

This drug is underinvestigation to treat malignant melanoma.

Recombinant Human Thrombopoietin

[A225691, A225696] This drug is used in the treatment of thrombocytopenia. … Recombinant human thrombopoietin is a full-length glycosylated cytokine produced by Chinese hamster ovary cells and is used to promote the generation of megakaryocytes and platelets.

Peginterferon alfacon-1

[Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients with chronic hepatitis C infections. … PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small

H3B-8800

H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551]. … H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine [L2551].

Rusalatide

TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified as the fibroblast high-affinity receptor binding domain.

Bevirimat

Bevirimat, also known as PA-457 or YK-FH312, is investigated in clinical trials for treating HIV infection. Bevirimat is a solid. … It is not currently FDA-approved, but is undergoing clinical trials conducted by the pharmaceutical company Panacos.