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Displaying results 6961 - 6970 of 10000 in total
  1. Drug

    Capadenoson

    go.drugbank.com/drugs/DB16118
    Investigational

    Capadenoson is under investigation in clinical trial NCT00518921 (Capadenoson in Angina Pectoris).

  2. Drug

    MGN-4893

    go.drugbank.com/drugs/DB17338
    Experimental

    MGN-4893 is an inhibitor of microRNA-451. In February 2011, it was granted FDA orphan designation for the treatment of polycythemia vera.[L47356]

  3. Drug

    Dipraglurant

    go.drugbank.com/drugs/DB12733
    Investigational

    Dipraglurant has been used in trials studying the treatment of Parkinson's Disease. It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).

  4. Drug

    Trifluoroethanol

    go.drugbank.com/drugs/DB03226
    Experimental

    It is also used in various pharmaceutical, chemical and engineering applications.

  5. Drug

    5-methoxy-N,N-dimethyltryptamine

    go.drugbank.com/drugs/DB14010
    IllicitInvestigational

    It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. … This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South America in religious and spiritual rituals.

  6. Drug

    Eperisone

    go.drugbank.com/drugs/DB08992
    Investigational

    It is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh. … Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and

  7. Drug

    Norfloxacin succinil

    go.drugbank.com/drugs/DB20858
    Experimental

    Norfloxacin succinil is a small molecule drug. The usage of the INN stem '-nil' in the name indicates that Norfloxacin succinil is a benzodiazepine receptor antagonist/agonist. … The usage of the INN stem '-oxacin' in the name indicates that Norfloxacin succinil is a nalidixic acid derivative antibacterial. Norfloxacin succinil has a monoisotopic molecular weight of 419.15 Da.

  8. Drug

    Bicuculline

    go.drugbank.com/drugs/DB11562
    Experimental

    It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors.

  9. Drug

    Ulixertinib

    go.drugbank.com/drugs/DB13930
    Investigational

    It is currently in clinical trials for the treatment of a wide range of tumors. … Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474].

  10. Drug

    Ontuxizumab

    go.drugbank.com/drugs/DB16270
    Investigational

    It is under investigation in clinical trial NCT01574716 (Sarcoma Study of Morab-004 Utilization: Research and Clinical Evaluation). … Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 (TEM-1).