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Displaying results 6961 - 6970 of 10000 in total
  1. Drug

    Enasidenib

    go.drugbank.com/drugs/DB13874
    ApprovedInvestigational

    Food and Drug Administration on August 1, 2017. … gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345].

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin-2-ylamino)propan-2-ol
  2. Drug

    Valopicitabine

    go.drugbank.com/drugs/DB13920
    Investigational

    The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. … Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-C-methylcytidine 3'-O-L-valinyl ester
  3. Drug

    Testosterone cypionate

    go.drugbank.com/drugs/DB13943
    ApprovedInvestigational

    Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Testosterone enanthate

    go.drugbank.com/drugs/DB13944
    ApprovedInvestigational

    As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659].

    Mixtures: NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Estradiol cypionate

    go.drugbank.com/drugs/DB13954
    ApprovedVet approved

    Estradiol Cypionate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body. … Because of the difference in potency between estradiol and estrone, menopause (and a change in primary hormone from estradiol to estrone) is associated with a number of symptoms associated with this reduction

    Mixtures: FEMELIN®, FEMELIN®Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  6. Drug

    Hycanthone

    go.drugbank.com/drugs/DB14061
    Experimental

    Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 3-RingSynonyms: 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one
  7. Drug

    p-Phenylenediamine

    go.drugbank.com/drugs/DB14141
    Approved

    Salts: p-Phenylenediamine dihydrochlorideCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  8. Drug

    Propylparaben

    go.drugbank.com/drugs/DB14177
    Approved

    Propylparaben is used in allergenic testing.

    Synonyms: n-Propyl 4-hydroxybenzoate, n-Propyl p-hydroxybenzoateCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Nickel sulfate

    go.drugbank.com/drugs/DB14180
    Approved

    Nickel sulfate is used in allergenic testing.

    Synonyms: Nickel sulfate(1:1)Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Cobalt chloride

    go.drugbank.com/drugs/DB14206
    Approved

    Synonyms: cobalt(2+) chlorideCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors