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Displaying results 61 - 70 of 12007 in total
  1. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    [L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045] … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.

    Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAIN, SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION.
  2. Drug

    Apadamtase alfa

    go.drugbank.com/drugs/DB15164
    ApprovedInvestigational

    Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency in ADAMTS13 is responsible for the microangiopathic complications associated with cTTP

    Categories: Amino Acids, Peptides, and Proteins, Enzymes and CoenzymesSynonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs
  3. Drug

    Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein

    go.drugbank.com/drugs/DB33819
    Experimental

    Synonyms: Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein
  4. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).

    Mixtures: HalfLytely and Bisacodyl, HalfLytely and BisacodylCategories: Alimentary Tract and Metabolism, Phenols
  5. Drug

    Idursulfase

    go.drugbank.com/drugs/DB01271
    ApprovedInvestigational

    Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various cell types … Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons.

    Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Alpha-L-iduronate sulfate sulfatase, Iduronate 2-sulfatase
  6. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    It serves as an acid moiety for anabolic steroid boldenone. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.

    Synonyms: Undecenoic acid, 10-undecenoic acidMixtures: Foot and Body Powder, Fungi Nail Toe and Foot MS
  7. Drug

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

    go.drugbank.com/drugs/DB18681
    Experimental

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. … It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
  8. Drug

    Salicylic acid

    go.drugbank.com/drugs/DB00936
    ApprovedInvestigationalVet approved

    A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions.

    Synonyms: Salicylic acid, 2-Hydroxybenzoic acidMixtures: Dermaharmony Sulfur and Salicylic Acid, Dermaharmony Sulfur and Salicylic Acid
  9. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. … Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes.

    Synonyms: 2-Acetoxybenzoic acid, acetyl salicylic acidInternational brands: Solprin acid
  10. Drug

    Gibberella fujikuroi

    go.drugbank.com/drugs/DB15511
    Approved

    Gibberella fujikuroi allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, fusarium moniliforme