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Losartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide.
Synonyms: (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol, 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazoleMixtures: ARAMAX ® 5/50 MG TABLETAS, ARAMAX ® 5/50 MG CAPSULASTolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnIt is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. … Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone, 3,4-dihydroxy-5-nitro-4'-methylbenzophenone5-O-phosphono-alpha-D-ribofuranosyl diphosphate
go.drugbank.com/drugs/DB01632ApprovedWithdrawnThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Synonyms: 5-Phosphoribosyl 1-pyrophosphate, 5-Phospho-alpha-D-ribose 1-diphosphatePrimidone
go.drugbank.com/drugs/DB00794ApprovedVet approved[L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione, 2-deoxyphenobarbitalSecobarbital
go.drugbank.com/drugs/DB00418ApprovedVet approvedSecobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties.
Synonyms: 5-allyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrioneCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2C8 InducersLatanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigationalAnother benefit latanoprost is that it can be administered once a day.[A184490] … Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998.
Synonyms: isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate, Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoateMixtures: Xalacom 50 Mikrogramm/ml + 5 mg/ml Augentropfen, LatanoTim-Vision 50 Mikrogramm/ml + 5 mg/ml AugentropfenAcetazolamide
go.drugbank.com/drugs/DB00819ApprovedInvestigationalVet approvedOne of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizur...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide, 5-acetamido-1,3,4-thiadiazole-2-sulfonamideCyproheptadine
go.drugbank.com/drugs/DB00434ApprovedInvestigationalCyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine, 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidineStreptococcus pneumoniae type 5 capsular polysaccharide antigen
go.drugbank.com/drugs/DB10323ApprovedInvestigationalStreptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 5 of *Streptococcus pneumoniae*.
Mixtures: SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION (MULTIDOSE - 5 DOSE), PNEUMOVAX 23 0,5 ML ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADETSynonyms: pneumococcal capsular polysaccharide type 5 vaccine, Streptococcus pneumoniae type 5 capsular polysaccharide antigenSumatriptan
go.drugbank.com/drugs/DB00669ApprovedInvestigationalSumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.
Synonyms: (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamideMixtures: TRASS® TABLETA RECUBIERTA, TRASS® TABLETA RECUBIERTA