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Displaying results 61 - 70 of 441 in total
  1. Drug

    Simoctocog alfa

    go.drugbank.com/drugs/DB09108
    Approved

    Simoctocog alfa is a fourth-generation BDD FVIII product made in the human embryonic kidney (HEK) cell line. … Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells.

    Synonyms: Simoctocog alfa
  2. Drug

    Dornase alfa

    go.drugbank.com/drugs/DB00003
    ApprovedInvestigational

    The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting intracellular DNA.

    Synonyms: Dornasa alfa, Dornase alfaCategories: dornase alfa (desoxyribonuclease)
  3. Drug

    Taliglucerase alfa

    go.drugbank.com/drugs/DB08876
    Approved

    Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase.

    Categories: taliglucerase alfaSynonyms: Taliglucerase alfa
  4. Drug

    Copper usnate

    go.drugbank.com/drugs/DB13830
    Experimental

    Categories: copper usnateSynonyms: Copper usnate
  5. Drug

    Cupric glycinate

    go.drugbank.com/drugs/DB11509
    ExperimentalVet approved

    Synonyms: Copper glycinate, Copper(II) biglycinate
  6. Drug

    Tividenofusp alfa

    go.drugbank.com/drugs/DB17628
    ApprovedInvestigational

    Developed by Denali Therapeutics, tividenofusp alfa received FDA approval on March 25, 2026, under the accelerated approval pathway [L56097, L56099]. … Tividenofusp alfa is a first-in-class, brain-penetrant enzyme replacement therapy (ERT) indicated for the treatment of Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome [L56097, L56099

    Synonyms: Tividenofusp alfa
  7. Drug

    Moroctocog alfa

    go.drugbank.com/drugs/DB13999
    Approved

    Use of recombinant DNA-derived clotting factor treatments, such as Moroctocog alfa, has reduced this risk. … Moroctocog alfa is produced through recombinant DNA technology and purification, resulting in a 1438 amino acid, 170 kDa protein [L41170].

    Synonyms: Moroctocog alfa
  8. Drug

    Thrombomodulin Alfa

    go.drugbank.com/drugs/DB05777
    Approved

    Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123).

    Synonyms: Thrombomodulin Alfa
  9. Drug

    Ferrous glycine sulfate

    go.drugbank.com/drugs/DB14501
    Approved

    Synonyms: Ferrous (II) Glycine Sulphate Complex
  10. Drug

    Asfotase alfa

    go.drugbank.com/drugs/DB09105
    ApprovedInvestigational

    Asfotase Alfa is marketed under the brand name Strensiq® by Alexion Pharmaceuticals, Inc. The annual average price of Asfotase Alfa treatment is $285,000. … Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP).

    Categories: asfotase alfaSynonyms: Asfotase alfa