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Mometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295]. … It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906].
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, HEXALER DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigationalMedroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.
Mixtures: DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET, DIVICONT TABLETAS 1 MG/5 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersEpinephrine
go.drugbank.com/drugs/DB00668ApprovedInvestigationalVet approvedOn August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353]. … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions.
Mixtures: SEPTANEST® ADRENALINEE AU 1/100.000, LOCANEST-A 40 MG/2ML + 0,025/2ML ENJEKSİYONLUK ÇÖZELTİ, 50 ADETCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigationalMetoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.
Synonyms: DL-metoprololMixtures: Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg, Implicor 50 mg/5 mg FilmtablettenMoclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalA reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. … Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901].
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Monoamine Oxidase A InhibitorsProducts: MOCLOBEMID-NEURAX 150 MG, Aurorix 150 mg - FilmtablettenAlbuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedThe R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity. … Salbutamol is formulated as a racemic mixture of the R- and S-isomers.
Mixtures: AXOL DUO, Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised InhalationCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsPosaconazole
go.drugbank.com/drugs/DB01263ApprovedInvestigationalVet approvedPosaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: POSACONAZOLE DR. REDDY'S (Posaconazole 100 mg Modified Release tablets), POSACONAZOLO DR. REDDY'SCyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalCyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt.
International brands: Cobolin-MMixtures: Vitamine Du Groupe B Plus Fer - Liq, PAGAMAX PLUS 150 MG/1 MG KAPSÜL ,60 KAPSÜLTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigational[T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms, or insomnia, which are commonly associated with SSRI and SNRI therapy. … [T646] Trazodone acts on various receptors, including certain histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a narrow range of neurotransmitters
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneMycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigational[A249175] This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. … Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone.
Categories: Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: MICOFENOLATO DE MOFETILO CAPSULAS 250 MG, CELLCEPT 500 MG FİLM KAPLI TABLET, 150 ADET