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Displaying results 61 - 70 of 1809 in total
  1. Drug

    Sotatercept

    go.drugbank.com/drugs/DB12118
    ApprovedInvestigational

    It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain.

    Synonyms: ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-
  2. Drug

    Valziflocept

    go.drugbank.com/drugs/DB17728
    Investigational

    Synonyms: Recombinant human soluble fc-gamma receptor iib, Fc.gamma.riib receptor (human soluble extracellular fragment)
  3. Drug

    4A10

    go.drugbank.com/drugs/DB18292
    Experimental

    Synonyms: Anti-interleukin-7 Receptor α Monoclonal antibody
  4. Drug

    Prolactin G129R

    go.drugbank.com/drugs/DB18431
    Investigational

    Synonyms: Prolactin receptor antagonist (Prolactin G129R)
  5. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    [A274098] It works by binding to the SARS-CoV-2 spike protein receptor binding domain (RBD), neutralize the virus and preventing its entry into the host cell.

    Synonyms: Immunoglobulin G1-lambda, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody, Immunoglobulin G1 [242-phenylalanine,243-glutamic acid,260-tyrosine,262-threonine,264-glutamic acid,339-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding
  6. Drug

    CLL1-CD33 compound chimeric antigen receptor T cells

    go.drugbank.com/drugs/DB18568
    Investigational

    Synonyms: CLL1-CD33 compound chimeric antigen receptor T cells, Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33
  7. Drug

    B7-H3-specific chimeric antigen receptor T cells

    go.drugbank.com/drugs/DB18567
    Experimental

    Synonyms: B7-H3-specific chimeric antigen receptor T cells, Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3
  8. Drug

    Nemvaleukin alfa

    go.drugbank.com/drugs/DB18187
    Investigational

    Synonyms: human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human interleukin 2 fragment (62-132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2, receptor α-chain fragment (139-303), produced in Ch
  9. Drug

    PA3-17

    go.drugbank.com/drugs/DB18569
    Investigational

    PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.

    Synonyms: Chimeric Antigen Receptor T Cells targeting CD7
  10. Drug

    OriCar-017

    go.drugbank.com/drugs/DB17280
    Investigational

    Synonyms: chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D (GPRC5D)