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Arbutin
go.drugbank.com/drugs/DB11217ApprovedExtracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal di...
Mixtures: Dr G Whitening REFORMER by EGF, Dr G Whitening FORTIFIER by EGFEmapalumab
go.drugbank.com/drugs/DB14724ApprovedInvestigationalEmapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018. … [L4840] As well, emapalumab was given the status of PRIME by the EMA.[L4845]
Cidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigational[FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]
Dorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: COSOPT 20MG/ML+5MG/ML, COSOPT 20MG/ML+5MG/MLProducts: TRUSOPT 20MG/ML, DORLAZEPT 20MG/MLHyaluronic acid
go.drugbank.com/drugs/DB08818ApprovedInvestigationalVet approvedHA is involved in many important physiological processes, including but not limited to wound healing, tissue regeneration, and joint lubrication. … [A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in oral, topical, and injectable forms.
Mixtures: Hyaluronic Acid 60mg and Lidocaine 2% PFProducts: HYALGAN 20MG/2ML INJECTIONTelithromycin
go.drugbank.com/drugs/DB00976ApprovedSimilar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. … Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.
Leflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Products: ARAVA 10MG, ARAVA 20MGTopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigational[A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. … [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel antidiabetic drug.[A188330]
Products: TOPAMAX 50MG, TOPIRAMAT AL 50MGEthchlorvynol
go.drugbank.com/drugs/DB00189ApprovedIllicitWithdrawnIt has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Isocarboxazid
go.drugbank.com/drugs/DB01247Approved[T115] It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.