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Abiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigationalAbiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis … [A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April,[A260880] July,[L47745] and September 2011,[A260880] respectively.
Synonyms: (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol, 17-(3-Pyridyl)androsta-5,16-dien-3beta-olCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesEnsulizole
go.drugbank.com/drugs/DB11115ApprovedEnsulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. … According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ranging between 74 and 148mM can be found in commercial sunscreen products [A27151].
Mixtures: Olay Professional ProX Age Repair SPF 30, g and h Protect BodyCategories: Heterocyclic Compounds, 2-RingIodine
go.drugbank.com/drugs/DB05382ApprovedInvestigationalIodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Mixtures: Prim - Royal P.M.T., Mega-vim 75 With Beta-carotene - TabletsProducts: Tincture Of Iodine 5%, JCI MN Colloidal Iodine Immune-improving WaterChloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approved[A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 was revoked on 15 June 2020. … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria.
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsSynonyms: N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamineCetuximab
go.drugbank.com/drugs/DB00002ApprovedInvestigational[A227963] EGFR is often mutated in certain types of cancer and serves as a driver of tumorigenesis. … colorectal cancer with a BRAF V600E mutation.
Products: ERBITUX ® 5 MG/ML, ERBITUX® 5 MG/MLTinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalIt is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. … It is an anticoagulant and considered an antithrombotic. Tinzaparin must be given either subcutaneously or parenterally.
Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INYECTABLE VIAL 2 ML. 20.000 UI/ML.Atezolizumab
go.drugbank.com/drugs/DB11595ApprovedInvestigationalAtezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers. … [L7489] Atezolizumab was granted FDA approval on 18 October 2016.
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: TECENTRIQ 1200 MG / 20 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 1200 MG/ 20 MLFesoterodine
go.drugbank.com/drugs/DB06702ApprovedFesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADET, FOSETAZ 8 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADETPrucalopride
go.drugbank.com/drugs/DB06480ApprovedInvestigational[A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018.[L4880] … Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties.
Categories: Serotonin 5-HT4 Receptor Agonists, Heterocyclic Compounds, 2-RingProducts: Resolor Film-coated Tablet 2 mg, RESOLOR ® TABLETAS RECUBIERTAS DE 2 MGLetermovir
go.drugbank.com/drugs/DB12070ApprovedInvestigationalLetermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. … [L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors.[A31290] Letermovir has recieved both priority and orphan drug status from the FDA.
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsProducts: PREVYMİS 240 MG FİLM KAPLI TABLET, 28 ADET, PREVYMİS 480 MG FİLM KAPLI TABLET, 28 ADET