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Lenvatinib
go.drugbank.com/drugs/DB09078ApprovedInvestigationalIn particular, VEGF has been identified as a crucial regulator of both physiologic and pathologic angiogenesis and increased expression of VEGF is associated with a poor prognosis in many types of cancers … These receptor tyrosine kinases (RTKs) located in the cell membrane play a central role in the activation of signal transduction pathways involved in the normal regulation of cellular processes, such as
Clopamide
go.drugbank.com/drugs/DB13792InvestigationalClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
Tesevatinib
go.drugbank.com/drugs/DB11973InvestigationalIn addition, tesevatinib inhibits EphB4, an RTK that is highly expressed in many human tumors and plays a role in promoting angiogenesis. … Tesevatinib inhibits the EGF, HER2, and VEGF RTKs, each of which is a target of currently approved cancer therapies.
Rebastinib
go.drugbank.com/drugs/DB13005InvestigationalIt is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
Glisoxepide
go.drugbank.com/drugs/DB01289InvestigationalGlisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake co...
Chromium picolinate
go.drugbank.com/drugs/DB11255ApprovedChromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. … Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss.
Categories: Compounds used in a research, industrial, or household settingCeforanide
go.drugbank.com/drugs/DB00923ApprovedIt has a longer elimination half-life than any currently available cephalosporin. … Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species
2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
go.drugbank.com/drugs/DB13869ExperimentalTIMBD is an azaresveratrol analog.
Pegargiminase
go.drugbank.com/drugs/DB06592InvestigationalPegargiminase is an anticancer agent.
Categories: Compounds used in a research, industrial, or household setting