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Londamocitinib
go.drugbank.com/drugs/DB19190InvestigationalLondamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high
Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-Quinupramine
go.drugbank.com/drugs/DB13246ApprovedQuinupramine has been approved in France under the brand name Kinupril, as an antidepressant [A175003].
Ledaborbactam etzadroxil
go.drugbank.com/drugs/DB21455InvestigationalLedaborbactam etzadroxil is a small molecule drug. The usage of the INN stem '-bactam' in the name indicates that Ledaborbactam etzadroxil is a ẞ-lactamase inhibitor. … Ledaborbactam etzadroxil is under investigation in clinical trial NCT06733675 (Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination).
CoVac-1
go.drugbank.com/drugs/DB16429InvestigationalSponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein[A226588]. … It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults (pVAC))[L30428] and aims to induce broad
Livmoniplimab
go.drugbank.com/drugs/DB18939InvestigationalLivmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination … With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Ivarimod
go.drugbank.com/drugs/DB19605ExperimentalIvarimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Ivarimod is a immunomodulator, both stimulant/suppressive and stimulant. … Ivarimod has a monoisotopic molecular weight of 512.33 Da.
Epertinib
go.drugbank.com/drugs/DB20062ExperimentalEpertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Epertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Epertinib has a monoisotopic molecular weight of 559.18 Da.
Quiflapon
go.drugbank.com/drugs/DB20376ExperimentalQuiflapon is a small molecule drug. The usage of the INN stem '-flapon' in the name indicates that Quiflapon is a 5-lipoxygenase-activating protein (FLAP) inhibitor. … Quiflapon has a monoisotopic molecular weight of 586.21 Da.
Burapitant
go.drugbank.com/drugs/DB20607ExperimentalBurapitant is a small molecule drug. The usage of the INN stem '-pitant' in the name indicates that Burapitant is a neurokinin NK1 (substance P) receptor antagonist. … Burapitant has a monoisotopic molecular weight of 681.2 Da.
Adarigiline
go.drugbank.com/drugs/DB21418ExperimentalAdarigiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Adarigiline is a monoamine oxydase (MAO)-inhibitor type B. … Adarigiline has a monoisotopic molecular weight of 360.08 Da.